Adoptive transfer of EBV|specific T cells results in sustained clinical ...

Adoptive transfer of EBV-specific T cells results in sustained clinical ...

Patients with recurrent or refractory Epstein Barr Virus (EBV)-positive nasopharyngeal carcinoma (NPC) continue to have poor outcomes.

Adoptive transfer of EBV-specific T cells results in sustained clinical ...

Abstract. Patients with recurrent or refractory Epstein Barr virus (EBV)-positive nasopharyngeal carcinoma (NPC) continue to have poor outcomes. Our earlier ...

Adoptive Transfer of EBV-specific T Cells Results in... - Lippincott

Although adoptive immunotherapy with EBV-CTLs for NPC has shown evidence of clinical activity in Phase I dose escalation studies,9,10 at present the overall ...

Adoptive transfer of EBV-specific T cells results in sustained clinical ...

Adoptive transfer of EBV-specific T cells results in sustained clinical responses in patients with locoregional nasopharyngeal carcinoma · Overview · Fingerprint ...

Adoptive transfer of EBV-specific T cells results in sustained clinical ...

Adoptive transfer of EBV-specific T cells results in sustained clinical responses in patients with locoregional nasopharyngeal carcinoma.

Adoptive Transfer of EBV-specific T Cells Results in Sustained ...

Request PDF | Adoptive Transfer of EBV-specific T Cells Results in Sustained Clinical Responses in Patients With Locoregional Nasopharyngeal Carcinoma ...

Adoptive T Cell Therapy for Epstein–Barr Virus Complications in ...

Adoptive T cell therapy with EBV-specific T cells is a promising therapeutic strategy for patients with PID both before and after HSCT.

Patient-tailored adoptive immunotherapy with EBV-specific T cells ...

... resulted in CR before EBV-CTL transfer in 2 of 5 patients. Related ... sustained EBV-specific T cell expansion after adoptive transfer (36).

Long-term outcome of EBV-specific T-cell infusions to prevent or ...

Long-term functionality. Change in the frequency of gene-marked cells in 46 peripheral blood samples from 18 patients before and after ex vivo stimulation with ...

Adoptive T-cell Transfer and Chemotherapy in the First-line ...

Adoptive immunotherapy with EBV-specific cytotoxic T lymphocytes (EBV-CTLs) has proven clinical efficacy, but it has never been evaluated in the ...

'Off-the-shelf' allogeneic antigen-specific adoptive T-cell therapy for ...

Conclusion These findings suggest that restriction switching by sequential infusion of allogeneic T-cell therapies that target EBV through distinct HLA alleles ...

Stem cell memory EBV-specific T cells control EBV tumor growth ...

Most clinical studies used EBV-CTLs generated by long-term expansion with continuous restimulation with EBV antigen–expressing lymphoblastoid ...

EBV-induced T-cell responses in EBV-specific and nonspecific ...

Encouragingly, promising clinical responses have been observed from adoptive cell transfer of EBV-specific T cells targeting latent antigens. Recent ...

Reconstitution of EBV-directed T cell immunity by adoptive transfer ...

Reconstitution of the T cell repertoire after allogeneic stem cell transplantation is a long and often incomplete process. As a result, reactivation of Epstein- ...

Epstein-Barr virus–specific T cell therapy for progressive multiple ...

CONCLUSION. EBV-specific adoptive T cell therapy was well tolerated. Clinical improvement following treatment was associated with the potency of ...

Adoptive immunotherapy with unselected or EBV-specific T cells for ...

DLIs and EBV-CTLs each induced durable complete or partial remissions in 73% and 68% of treated patients including 74% and 72% of patients ...

Virus-Specific T Cells for the Treatment of Systemic Infections ...

A promising strategy to rapidly restore antiviral immunity is the adoptive transfer of virus-specific T cells (VST). This therapy involves the ...

Redirecting T Cells against Epstein–Barr Virus Infection and ... - MDPI

some of these, the adoptive transfer of EBV specific T cells has been therapeutically explored, with clinical success. In order to avoid naturally occurring ...

Adoptive T‐cell therapy targeting Epstein–Barr virus as a treatment ...

This adoptive immunotherapy has also been shown to be safe with encouraging clinical responses. Allogeneic EBV T-cell therapy overcomes some of ...

Adoptive cellular immunotherapy for Epstein-Barr virus-associated ...

First successes with adoptive immunotherapy were described using donor lymphocyte infusion for the treatment of EBV+ PTLD in hematopoietic stem cell ...