Adrenergic signaling regulation of macrophage function

Adrenergic signaling regulation of macrophage function - PubMed

Macrophages are immune cells that are widespread throughout the body and critical for maintaining tissue homeostasis.

Adrenergic signaling regulation of macrophage function: do we ...

In this review, we discuss how activation of adrenergic receptors modulates macrophage effector functions and its implications for inflammatory responses and ...

Adrenergic modulation of neutrophil and macrophage functions

Most of these studies indicate that adrenergic signaling is able to regulate neutrophil functions, mainly through the engagement of β2AR. However, adrenergic ...

Adrenergic Regulation of Macrophage-Mediated Innate ...

Thus, activation of β2 adrenergic receptors in monocytes is usually anti-inflammatory, and β2 adrenergic receptor dysregulation in microglia and astrocytes may ...

(PDF) Adrenergic Signaling Regulation Of Macrophage Function

Macrophage beta2-adrenergic receptor is dispensable for the adipose tissue inflammation and function ... Objective Neuroimmune interactions ...

"α-Adrenergic receptor expression and regulation on the surface of ...

Macrophages play an integral role in eliminating infection during the inflammatory response. Catecholamines are known to alter macrophage function by ...

Adrenergic Regulation of Cardiac Macrophages - Scilight Press

Thus, macrophages have emerged as potential therapeutic targets for multiple cardiac diseases. Upon sympathetic activation, adrenergic/ cyclic ...

Adrenergic receptors regulate macrophage secretion - ScienceDirect

Abstract. Macrophages have been shown to possess both α2 and β2-adrenergic receptors which appear to antagonize each other. The ability of these two kinds of ...

β‐Adrenergic Receptor Signaling Reduces Pro‐Inflammatory ...

Catecholamines alter macrophage function by binding to adrenergic receptors on the cell membrane. Stimulation through β2-adrenergic ...

Adrenergic Signaling: A Targetable Checkpoint Limiting ... - Frontiers

That activity of innate immune cells is regulated by activation of ARs has been clearly demonstrated. Adrenergic signaling affects macrophage polarization and ...

Adrenergic signaling regulation of macrophage function: do we ...

Catecholamines (noradrenaline and adrenaline) activate α and β adrenergic receptors expressed by macrophages and shape the effector functions of these cells in ...

Stress hormone signaling through β‐adrenergic receptors regulates ...

β-AR signaling induces molecular changes in macrophages, including up-regulation of immune receptor CD14 and increased secretion of cytokines ...

Adrenergic receptor expression on RAW264.7 macrophages

In this study, AR surface expression patterns and regulation via AR-catecholamine interactions were characterized. Macrophage function was shown to be ...

Activation of Sympathetic Signaling in Macrophages Blocks...

This study shows that activation of β2-adrenergic receptor (Adrb2) signaling in macrophages induces the expression of T cell Ig and mucin domain 3 (Tim3), ...

Adrenergic Signaling in Muscularis Macrophages Limits ... - Cell Press

Myeloid-specific targeting of β2-AR, as well as arginase 1 (Arg1), coupled with pharmacological rescue experiments and exogenous activation of ...

Adrenergic regulation of immune cell function and inflammation

Immune cells respond by activation of adrenergic receptors, primarily the β2-adrenergic receptor, which signal through heterotrimeric G-proteins ...

β2-Adrenergic Receptor Enhances the Alternatively Activated ...

The autonomic nervous system has been studied for its involvement in the control of macrophages; however, the mechanisms underlying the ...

Acetylcholine‐synthesizing macrophages in subcutaneous fat are ...

These cells secrete acetylcholine to regulate the activation of thermogenic adipocytes, and their activity is controlled via adrenergic ...

Induction of M2 Regulatory Macrophages through the β2-Adrenergic ...

Taken together, these results demonstrate a role for β2-adrenergic receptor activation by catecholamines in promoting the M2 regulatory ...

Acetylcholine-synthesizing macrophages in subcutaneous fat are ...

These cells secrete acetylcholine to regulate the activation of thermogenic adipocytes, and their activity is controlled via adrenergic signaling through the β2 ...