Advances in Preclinical Research Models of Radiation|Induced ...

Advances in Preclinical Research Models of Radiation-Induced ...

An understanding of the biological pathways and mechanisms involved in normal tissue toxicity from RT will improve future cancer treatments by ...

Preclinical models of radiation-induced cardiac toxicity - Frontiers

Despite the advances in the delivery of thoracic radiation therapy, radiation-induced heart disease constitutes a growing clinical issue that severely ...

[PDF] Advances in Preclinical Research Models of Radiation ...

Advances in Preclinical Research Models of Radiation-Induced Cardiac Toxicity · R. Schlaak, G. SenthilKumar, +1 author. C. Bergom · Published in Cancers 1 ...

Advances in preclinical research models of radiation-induced ...

Fingerprint. Dive into the research topics of 'Advances in preclinical research models of radiation-induced cardiac toxicity'. Together they form a unique ...

Preclinical Models for Translational Research Should Maintain Pace ...

Acknowledging the unique capabilities of state-of-the-art preclinical radiation delivery machines is instrumental in the advancement of translational research.

Article Versions Notes - MDPI

Advances in Preclinical Research Models of Radiation-Induced Cardiac Toxicity. Cancers 2020, 12, 415. https://doi.org/10.3390/cancers12020415. AMA Style.

Preclinical radiotherapy - Nature

With recent improvements in precision-based small animal imaging modalities, micro-irradiation devices, and cancer models, preclinical radiotherapy studies have ...

Model Selection for the Preclinical Development of New Drug ...

Radiotherapy plays an essential role in the treatment of more than half of all patients with cancer. In recent decades, advances in devices that deliver ...

Radiotherapy in preclinical animal models - BioMed Central

Guest Edited by Dr Kirsten Lauber. Radiotherapy is a central element of multimodal cancer treatment, which has experienced tremendous advancements in the ...

FLASH forward to an ultra-fast new form of radiation - Penn Medicine

The research builds on Penn Medicine's preclinical research of FLASH radiation, with the goal of launching human clinical trials in late 2024.

Preclinical Ultra-High Dose Rate (FLASH) Proton Radiation Therapy ...

Animal studies with ultrahigh dose-rate radiation therapy (FLASH, >40 Gy/s) preferentially spare normal tissues without sacrificing antitumor efficacy ...

FLASH Proton Radiation Therapy Mitigates Inflammatory and ...

In recent years, multiple preclinical studies have suggested that delivering RT at high dose rates (termed “FLASH” RT), can improve the therapeutic index by ...

The preclinical gap in pancreatic cancer and radiotherapy

Refinement of radiotherapy delivery in the clinic also offers new opportunities, but these should be accompanied by mechanistic studies in the ...

Image-guided radiation therapy of tumors in preclinical models

Technological advances, including IGRT, allow for more conformal delivery of ionizing radiation that allows dose-escalation to tumors and/or enhanced sparing of ...

Understanding the impact of radiation-induced lymphopenia

The development of radiation-induced RIL preclinical models could help to establish a causative relationship between RIL and immunotherapy ...

Radiation-induced bystander and abscopal effects - Nature

Radiotherapy is a pivotal component in the curative treatment of patients with localised cancer and isolated metastasis, as well as being ...

Roadmap for precision preclinical x-ray radiation studies - IOPscience

It is mostly focused on models for cancer and normal tissue response to radiation, but also discusses other disease models. The recent technological evolution ...

(PDF) Preclinical models of radiation-induced cardiac toxicity

This review offers an insight into the existing preclinical models to study RIHD and the suggested mechanisms of RIMF, as well as available ...

Preclinical models in radiation oncology - BioMed Central

Preclinical models in radiation oncology are essential tools for cancer research and therapeutics. Various model ... advances in preclinical ...

The State of Preclinical Modeling for Early Phase Cancer Trials ...

We aimed to evaluate approaches cancer researchers used to justify advancing new combinations of molecularly targeted agents and radiation ...