Advancing Bispecific Antibodies

Bispecific antibodies: advancing precision oncology: Trends in Cancer

Highlights. Bispecific antibodies (bsAbs) offer a novel approach to anticancer therapy by targeting different antigens via a range of mechanisms ...

Bispecific antibodies: advancing precision oncology - ScienceDirect

BsAbs have shown high clinical efficacy in R/R hematological malignancies, with rapid developments across this field. Multiple clinical investigations are ...

Bispecific antibodies: advancing precision oncology - PubMed

Bispecific antibodies (bsAbs) are engineered molecules designed to target two different epitopes or antigens. The mechanism of action is ...

Advancing Multispecific Antibodies and Combination Therapy to the ...

Combining bispecific antibodies with ADCs; Exploring use in non-cancer indications including infectious disease and autoimmune; Incorporating pretargeting ...

Advancing Bispecific Antibodies and Combination Therapy to the ...

Tissue-restricted immune modulators may provide better therapeutic approaches to autoimmune disease. We are developing bispecifics consisting of a high affinity ...

Advancing Collaborative Care of Multiple Myeloma With Bispecific ...

Bispecific antibodies (bsAbs) are a promising novel treatment approach for relapsed/refractory multiple myeloma (MM), but carry the risk of infectious adverse ...

Advancing Multispecifics & Combination Therapy - PEGS Europe

... Therapy track discusses translational approaches and optimization of candidates so they can advance them to successful bispecific antibody therapeutics.

Advancing bispecific antibodies | Drug Discovery News

Advancing bispecific antibodies · Antibodies that simultaneously target two distinct antigens overcome cancer therapy resistance by addressing antigenic ...

Current landscape and future directions of bispecific antibodies in ...

Recent advances in cancer immunotherapy using monoclonal antibodies have dramatically revolutionized the therapeutic strategy against advanced malignancies, ...

Bispecific antibodies: advancing precision oncology - Cell Press

(B) Monoclonal antibodies (mAbs) are monospecific toward one epitope of a single antigen. (C) Bispecific antibodies (bsAbs) with distinct antigen-binding ...

BioNTech oncology acquisition to advance bispecific antibodies

BioNTech SE has agreed to acquire Biotheus and will gain rights to the biotech's in-house bispecific antibody drug conjugate (ADC) capability ...

Bispecific Antibody Engineering - Genedata

Advancing Bispecific Antibody Discovery. Genedata Biologics® enables the systematic design, cloning, and testing of large numbers of bi- and multi-specifics ...

Advancing Clinical Practices for Administration of Bispecifics

Bispecific Antibodies: Operationalizing Administration and Follow-Up : Episode 6. Advancing Clinical Practices for Administration of Bispecifics.

Marengo Therapeutics Advancing Bispecific Antibody to Phase II ...

NEW YORK – Marengo Therapeutics' bispecific antibody, invikafusp alfa, showed potential as treatment for certain cancer patients who have ...

Engineering the Next Generation of Bispecific Antibodies

NEXT-GENERATION IMMUNOTHERAPY. 09:00. Advancing Cancer Immunotherapy: Next-Generation T Cell Engagers Targeting CLDN6 via CD3/CD137 Binding.

Advancing Early-Stage Bispecific Discovery Programs Towards ...

Watch this webinar with Dr. Jin Lu to learn how Lonza's novel expression tools can advance your bispecific antibody discovery programs.

Gritstone Oncology Advances Solid Tumor Bispecific Antibody ...

It is advancing its bispecific antibody (BiSAb) program under the direction of newly appointed vice president of Antibody Therapeutics, Jonah Rainey, Ph.D.

AACR 2021: Advancing Bispecific Antibody Discovery using a ...

RenLiteTM mouse carries full human heavy chain VDJ loci and a fixed common human light chain VJ gene. The derived antibodies share the same light chain with ...

Bispecific Antibodies are Helping to Advance the Field of Lymphoma

Julie M. Vose, MD, MBA, and Avyakta Kallam, MD, spoke with CancerNetwork® about their research focusing on the use of bispecific antibodies.

A pivotal decade for bispecific antibodies? - Taylor & Francis Online

Bispecific antibodies (bsAbs) are a class of antibodies that can mediate novel mechanisms of action compared to monospecific monoclonal antibodies (mAbs).