Age|Associated Mitochondrial Dysfunction Accelerates Atherogenesis

Age-Associated Mitochondrial Dysfunction Accelerates Atherogenesis

Methods and Results: We analyzed the aortas of young and aged normolipidemic wild type, disease-free mice and found that aging led to elevated ...

Age-Associated Mitochondrial Dysfunction Accelerates Atherogenesis

We analyzed the aortas of young and aged normolipidemic wild type, disease-free mice and found that aging led to elevated IL (interleukin)-6 ...

Age-Associated Mitochondrial Dysfunction Accelerates Atherogenesis.

Age-Associated Mitochondrial Dysfunction Accelerates Atherogenesis. uri icon · Overview · Research · Identity · Additional Document Info ...

Mitochondrial dysfunction and its association with age-related ...

Decreased mitophagy has been reported to contribute to the pathogenesis of several age-associated disorders such as Parkinson's disease, Alzheimer's disease, ...

Ageing and atherosclerosis: vascular intrinsic and extrinsic factors ...

Disease-free, normolipidaemic mice develop mitochondrial dysfunction in the aorta as they age, first detected at 11 months of age (measured as a ...

New insights into vascular aging: Emerging role of mitochondria ...

Mitochondrial dysfunction also contributes to other age-related molecular and cellular mechanisms, such as crosstalk with telomeres, senescence-associated ...

Age-Associated Mitochondrial Dysfunction Accelerates Atherogenesis

Many age-related disorders are associated with mitochondrial dysfunction, measured by reduced energy production, structural damage to cellular components, and ...

Mitochondrial Aging and Age‐Related Dysfunction of Mitochondria

Premature or accelerated vascular aging and atherosclerosis can be associated with dysfunction of mitochondria [33, 34]. It is well known ...

The role of mitochondrial dysfunction in age-related diseases

Current evidence points to mitochondrial dysfunction as an overarching mechanism of aging and age-related disease. It is implicated in an extensive list of ...

Cardiovascular aging: spotlight on mitochondria

Endothelial dysfunction is also linked, and considered an antecedent to, other cardiovascular diseases including hypertension and ischemic heart disease (50, 51) ...

Vascular Aging and Atherosclerosis: A Perspective on Aging

... accelerates age-related endothelial dysfunction [152]. In addition ... Age-Associated Mitochondrial Dysfunction Accelerates Atherogenesis. Circ Res ...

Age-Associated Mitochondrial Dysfunction Accelerates Atherogenesis

Dive into the research topics of 'Age-Associated Mitochondrial Dysfunction Accelerates Atherogenesis'. Together they form a unique fingerprint. Sort by; Weight ...

Mitochondria in vascular disease - Oxford Academic

While there is increasing evidence of mitochondrial dysfunction in atherosclerosis, it is not clear whether this is a consequence of the disease or that both ...

Building the case for mitochondrial transplantation as an anti-aging ...

Mitochondrial dysfunction is a common denominator in both biological aging and cardiovascular disease (CVD) pathology.

Aging and aging-related diseases: from molecular mechanisms to ...

Additionally, it is associated with the development of many chronic diseases, including cardiovascular disease and neurodegenerative disorders.

Targeting mitochondrial fitness as a strategy for healthy vascular aging

Accumulating evidence also indicates that mitochondrial oxidative stress and associated impairments in mitochondrial fitness underlie the vascular dysfunction ...

Mitophagy in atherosclerosis: from mechanism to therapy - Frontiers

... dysfunctions of mitochondria-associated endoplasmic reticulum contacts in atherosclerosis ... Age-associated mitochondrial dysfunction accelerates atherogenesis.

Role of mitochondrial dysfunction and altered autophagy in ...

Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics. Emanuele Marzetti,; Anna Csiszar, ...

Decoding vascular aging: implications for atherosclerosis ...

Age-related pathologies, particularly cardiovascular disorders ... DNA damage links mitochondrial dysfunction to atherosclerosis and the metabolic syndrome.

Role of PTEN-Induced Protein Kinase 1 as a Mitochondrial ...

Mitochondrial dysfunction is a well-known hallmark of heart diseases, including ischemic heart disease (IHD) [25]. Ischemic damage can cause ...