Aging Affects KV7 Channels and Perivascular Adipose ...

Aging Affects KV7 Channels and Perivascular Adipose Tissue ...

Aging is an independent risk factor for hypertension, cardiovascular morbidity, and mortality. However, detailed mechanisms linking aging to ...

Aging affects KV7 channels and perivascular-adipose tissue ...

We found that Kcnq1,3,4,5 mRNA expression was unchanged in the arteries during aging. These RNA-seq findings were confirmed by qPCR. Thus, we ...

Aging affects KV7 channels and perivascular-adipose tissue ...

Aging affects KV7 channels and perivascular-adipose tissue-mediated vascular tone. 1Yibin Wang, 2Fatima Yildiz, 3Andrey Struve, 1,4 Mario ...

SUPPLEMENTARY MATERIAL Aging Affects KV7 Channels and ...

Aging Affects KV7 Channels and Perivascular Adipose Tissue-Mediated. Vascular Tone. Figure S1. Page 2. Figure S1. Aging-effects KV7 regulation of membrane ...

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(PDF) Aging Affects KV7 Channels and Perivascular Adipose Tissue ...

Results revealed impaired perivascular adipose tissue-mediated control of vascular tone particularly via KV7.3–5 channels with increased age ...

[PDF] Aging Affects KV7 Channels and Perivascular Adipose Tissue ...

The data suggest that targeting inflammation and metabolism in perivascular adipose tissue could represent novel approaches to restore vascular function ...

Aging Affects K_V7 Channels and Perivascular Adipose ...

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Aging affects KV7 channels and perivascular-adipose ... - Altmetric

Aging affects KV7 channels and perivascular-adipose tissue-mediated vascular tone · bioRxiv, April 2021 · 10.1101/2021.04.11.438975 · Yibin Wang, Fatima Yildiz, ...

Aging Affects KV7 Channels and Perivascular Adipose Tissue ...

Aging Affects KV7 Channels and Perivascular Adipose Tissue-Mediated Vascular Tone ... Authors: Yibin Wang; Fatima Yildiz; Andrey Struve; Mario Kassmann; Lajos ...

Aging Affects KV7 Channels and Perivascular Adipose Tissue ...

We studied the aging effects on the role of perivascular adipose tissue and downstream vasoconstriction targets, voltage-dependent KV7 channels, and their ...

KCNQ5 Controls Perivascular Adipose Tissue–Mediated Vasodilation

We show that PVAT causes smooth muscle cell KV7.5 family of voltage-gated potassium (K+) channels to hyperpolarize the membrane potential. This ...

Perivascular adipose tissue: Fine-tuner of vascular redox status and ...

Aging affects KV7 channels and perivascular adipose tissue-mediated vascular tone ... effects of perivascular adipose tissue in high-fat diet obese mice. Br ...

KCNQ5 Controls Perivascular Adipose Tissue–Mediated Vasodilation

Aging affects Kv7 channels and perivascular adipose tissue-mediated vascular tone. Front Physiol. 2021;12:749709. doi: 10.3389/fphys ...

Perivascular adipose tissue and the dynamic regulation of Kv7 and ...

Interestingly, these channels are unique among VSMC potassium channels. First, both have been implicated in the control of microvascular tone by ...

Reduced anti-contractile effect of perivascular adipose tissue on ...

Our results suggest that the reduced anti-contractile effect of PVAT in SHR correlates with a deficiency in Kv7 channels. Diffusion hindrance of PVAT is also a ...

Influence of Age on Anticontractile Effect of Perivascular Adipose ...

Perivascular adipose tissue (PVAT) and its vasomodulatory effects play an important role in the physiology and pathophysiology of blood ...

The altered differentiation of old perivascular adipose tissue‐derived...

We studied the aging effects on the role of perivascular adipose tissue and downstream vasoconstriction targets, voltage-dependent KV7 channels, and their ...

The Kv7 Channel and Cardiovascular Risk Factors - Frontiers

The vasodilatory effect of perivascular relaxing factors (PVRFs) released by perivascular adipose tissue (PVAT) may be mediated through opening of Kv7. The ...

[PDF] Palmitic Acid Methyl Ester and Its Relation to Control of Tone ...

Aging Affects KV7 Channels and Perivascular Adipose Tissue-Mediated Vascular Tone · Medicine, Biology. bioRxiv · 2021.