Airway Smooth Muscle Cell Mitochondria Damage and Mitophagy in ...

Chronic obstructive pulmonary disease (COPD) is characterized by irreversible deterioration of the airway wall. Cigarette smoking is the ...

Cigarette smoking is the major trigger, and in vitro studies showed that cigarette smoke extract (CSE) induced mitophagy in airway epithelial ...

Mitochondrial Transfer between Airway Cells: Helping the ... - NCBI

Mitochondrial dysfunction has been associated with aging and diverse chronic lung pathologies (1). Cells with high energy demand are more ...

TNF alpha induces mitophagy in human airway smooth muscle cells

We observed that TNFα and FCCP treatment increased lysosomal volume density and mitochondrial colocalization with lysosomes in hASM cells, ...

Mitochondrial dysfunction in lung ageing and disease

The behaviour and proliferation of airway smooth muscle (ASM) cells are dependent on mitochondrial activity and contribute to the pathogenesis of asthma by ...

Mitochondrial influences on smooth muscle phenotype

Mitochondria also can signal to adjacent cells by contributing to the content of exosomes. Considering these and other mechanisms, it is ...

Mitochondrial regulation of airway smooth muscle functions in health ...

Mitochondria are important for airway smooth muscle physiology due to their diverse yet interconnected roles in calcium handling, ...

Mitochondrial Transfer Regulates Bioenergetics in Healthy and ...

Mitochondrial dysfunction has been reported in chronic obstructive pulmonary disease (COPD). Transfer of mitochondria from mesenchymal stem ...

Airway Smooth Muscle Cell Mitochondria Damage and Mitophagy in ...

Chronic obstructive pulmonary disease (COPD) is characterized by irreversible deterioration of the airway wall. Cigarette smoking is the major trigger, ...

Mitochondria are involved in bronchial smooth muscle remodeling in ...

BSM mass, cell proliferation, ATP content, mitochondrial respiration, mass and biogenesis, and calcium response were all increased in ...

Multifaceted roles of mitochondria in asthma | Cell Biology and ...

Furthermore, exposure of asthmatic airway smooth muscle cells (ASMCs) to CS extract (CSE) has been shown to exacerbate mitochondrial ...

Altered mitochondrial reactive oxygen species (ROS) production in ...

Introduction: Increased airway smooth muscle cell (ASMC) mass is a feature of airway remodelling is correlated with asthma severity.

Regulation of mitochondrial transfer between airway smooth muscle ...

Mitochondrial transfer between stem cells and damaged airway smooth muscle cells (ASMC) can reverse the inflammatory consequences of mitochondrial dysfunction ( ...

Oxidative stress–induced mitochondrial dysfunction drives ...

Mechanisms of allergy and clinical immunology. Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in ...

Mitochondrial dysfunction in airways and quadriceps muscle of ...

Mitochondrial damage and dysfunction have been reported in airway and quadriceps muscle cells of patients with chronic obstructive pulmonary ...

The role of mitochondria in eosinophil function - Frontiers

Mitochondrial dysfunction and altered metabolism have been observed in airway epithelial and smooth muscle cells from patients with asthma. However, the role of ...

Mitochondrial regulation of airway smooth muscle functions in health ...

Mitochondria are important for airway smooth muscle physiology due to their diverse yet interconnected roles in calcium handling, redox regulation, ...

Inflammation-Induced Protein Unfolding in Airway Smooth Muscle ...

Reduced Mfn2 also disrupts mitochondrial tethering to the ER, thereby decreasing mitochondrial Ca2+ influx. Increased PGC1α also promotes mitochondrial ...

Azithromycin induces apoptosis in airway smooth muscle cells ...

In summary, this study demonstrated that decreased ASMC apoptosis, higher mitochondrial membrane potential, and lower expression levels of mitochondrial ...

Hypermethylation of mitochondrial DNA in vascular smooth muscle ...

Vascular smooth muscle cell (SMC) from arterial stenotic-occlusive diseases is featured with deficiency in mitochondrial respiration and ...