- Airway epithelial compression promotes airway smooth muscle ...🔍
- Airway epithelial cells promote in vitro airway smooth muscle cell ...🔍
- Airway Epithelial Cells Drive Airway Smooth Muscle Cell Phenotype ...🔍
- Asthmatic and Normal Respiratory Epithelial Cells Respond ...🔍
- Bronchial epithelial and airway smooth muscle cell interactions in ...🔍
- Airway smooth muscle pathophysiology in asthma🔍
- Airway Epithelium Stimulates Smooth Muscle Proliferation🔍
- Putting the Squeeze on Airway Epithelia🔍
Airway epithelial compression promotes airway smooth muscle ...
Airway epithelial compression promotes airway smooth muscle ...
Our results provide mechanistic evidence that ET-1 secreted by compressed HBE cells in turn induces and sustains HASM cell contraction, as a direct consequence ...
Airway epithelial compression promotes airway smooth muscle ...
During acute bronchoconstriction, the airway epithelium becomes mechanically compressed, as airway smooth muscle contracts and the airway ...
Airway epithelial cells promote in vitro airway smooth muscle cell ...
Airway smooth muscle cells (ASMCs) play a key role in regulating airway tone and airflow, while abnormal ASMCs proliferation contributes to ...
Airway Epithelial Cells Drive Airway Smooth Muscle Cell Phenotype ...
The increased mass of airway smooth muscle (ASM) in the airways of asthmatic patients may contribute to the pathology of this disease by ...
Airway epithelial compression promotes airway smooth muscle ...
Request PDF | On Aug 2, 2018, Bo Lan and others published Airway epithelial compression promotes airway smooth muscle proliferation and contraction | Find, ...
Asthmatic and Normal Respiratory Epithelial Cells Respond ...
Several studies have shown that compressive force comparable with that arising in vivo, with bronchoconstriction, promotes bronchial epithelial cell activation ...
Bronchial epithelial and airway smooth muscle cell interactions in ...
Bronchial epithelial cells and airway smooth muscle cells and their crosstalk play a significant role in the pathogenesis of these diseases. Thus, targeting the ...
Airway smooth muscle pathophysiology in asthma
The airway smooth muscle (ASM) cell plays a central role in the pathogenesis of asthma and constitutes an important target for treatment.
Airway Epithelium Stimulates Smooth Muscle Proliferation
The airway epithelium modulates smooth muscle cell proliferation via a mechanism that involves secretion of soluble mediators including ...
muscle mass and promotes bronchial smooth- muscle cell proliferation and ... Bronchial epithelial compression regulates epider- mal growth factor ...
Airway epithelial cells promote in vitro airway smooth muscle cell ...
The proliferation of airway smooth muscle cells plays a very important role in pathological changes, and the reasons for ASMC proliferation are ...
Airway epithelial compression promotes airway smooth muscle ...
Our data demonstrate that mechanical compression of bronchial epithelial cells contributes to proliferation and basal contraction of airway smooth muscle cells ...
Airway mechanical compression: its role in asthma pathogenesis ...
These studies have demonstrated that mechanical forces can contribute to changes within the epithelial and other structural cells of the airway, ...
Targeting Airway Smooth Muscle Hypertrophy in Asthma - JAA
In vitro models show that acutely compressed airway epithelial cells release factors that stimulate increased basal ASM contraction and ...
Airway Epithelial Cells Drive Airway Smooth Muscle Cell Phenotype ...
Co-culture data indicate that the airway epithelium-induced proliferative phenotype of ASMCs is not driven by EGFR signaling, but rather may be dependent on ...
The Aftermath of Bronchoconstriction | ASME J. of Medical Diagnostics
Bronchoconstriction can recapitulate key phenotypic changes of asthmatic airway remodeling through mechanical compression on epithelium. These changes include ...
Airway remodelling in asthma and the epithelium: on the edge of a ...
ASM: airway smooth muscle; EMT: epithelial-to-mesenchymal transition; IL: interleukin; MMP: matrix metalloproteinase; TGF: transforming growth factor; TSLP: ...
ates a program which appears to promote asthma pathogenesis, including goblet cell hyperplasia, sub-‐epithelial fibrosis, and airway smooth muscle ...
Crosstalk of Airway Smooth Muscle and Epithelial Cells in Chronic ...
Airway epithelial compression promotes airway smooth muscle proliferation and contraction. American Journal of Physiology-Lung Cellular and ...
Bronchoconstriction: a potential missing link in airway remodelling
A growing body of literature indicates that airway epithelial cells cause pathophysiological processes when functionally altered by mechanical ...