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Airway smooth muscle in the pathophysiology and treatment of asthma


Airway smooth muscle in the pathophysiology and treatment of asthma

Airway smooth muscle (ASM) plays an integral part in the pathophysiology of asthma. It is responsible for acute bronchoconstriction, which is potentiated by ...

Airway smooth muscle pathophysiology in asthma

The airway smooth muscle (ASM) cell plays a central role in the pathogenesis of asthma and constitutes an important target for treatment.

Airway smooth muscle pathophysiology in asthma - ScienceDirect.com

The airway smooth muscle (ASM) cell plays a central role in the pathogenesis of asthma and constitutes an important target for treatment.

Airway smooth muscle function in asthma - Frontiers

Airway smooth muscle (ASM) is the major effector of exaggerated airway narrowing and AHR and many factors may contribute to its altered function in asthma.

Airway smooth muscle in the pathophysiology and treatment of ...

Airway smooth muscle (ASM) plays an integral part in the pathophysiology of asthma and is an important target in the treatment of asthma.

(PDF) Airway Smooth Muscle in the Pathophysiology and Treatment ...

00950.2012.-Airway smooth muscle (ASM) plays an integral part in the pathophysiology of asthma. It is responsible for acute bronchoconstriction, which is ...

Treating asthma means treating airway smooth muscle cells

In the present paper, studies will be discussed that have led to a novel view of the role of airway smooth muscle in the pathogenesis of asthma in which airway ...

The Pivotal Role of Airway Smooth Muscle in Asthma Pathophysiology

The pathophysiology of asthma is characterized by the association of airway hyperresponsiveness (AHR), inflammation, and remodelling [1–3]. AHR ...

Airway smooth muscle as a target of asthma therapy: history and ...

Ultimately, asthma is a disease characterized by constriction of airway smooth muscle (ASM). The earliest approach to the treatment of ...

Airway Smooth Muscle as a Target for Asthma Therapy

The precise role of airway smooth muscle in the pathogenesis of asthma remains uncertain. The contraction of airway smooth muscle certainly ...

Pathophysiology of bronchial smooth muscle remodelling in asthma

The smooth muscle also contributes to bronchial inflammation by secreting a range of inflammatory mediators, recruiting and activating inflammatory cells, such ...

Airway Smooth Muscle as a Target for Asthma Therapy

The precise role of airway smooth muscle in the pathogenesis of asthma remains uncertain. The contraction of airway smooth muscle certainly causes acute ...

Cellular sources of airway smooth muscle cells in asthmatic airway ...

Glucocorticoids and bronchodilators are currently routine treatments for asthma and can significantly improve some airway inflammation and ...

Airway Smooth Muscle as a Target of Glucocorticoid Action in the ...

Glucocorticoids are the most effective therapy currently available for the treatment of asthma. Glucocorticoids act primarily as anti-inflammatory agents in ...

Bronchial smooth muscle cell in asthma: where does it fit?

Asthma is a frequent respiratory condition whose pathophysiology relies on altered interactions between bronchial epithelium, smooth muscle ...

Increased airway smooth muscle cells in asthma: mechanisms and ...

In addition, an increased airway smooth muscle mass at preschool age is predictive of asthma at school age (6), and is associated with decreased lung function, ...

Origins of increased airway smooth muscle mass in asthma

There is broad agreement that, in asthma, increased airway smooth muscle mass, in part due to smooth muscle hyperplasia, is a very significant ...

Airway Smooth Muscle, Airway Remodeling & Angiogenesis

The beneficial effect of bronchial thermoplasty in reducing asthma symptoms, together with the increased potential of ASM cells of asthmatics to ...

Airway smooth muscle in asthma - Johns Hopkins University

Airway smooth muscle plays a multifaceted role in the pathogenesis of asthma. We review the current understanding of the contribution of airway myocytes to ...

Asthma Pathophysiology

Airway Muscle: the thin layer of muscle within the wall of an airway can contract to make it tighter and narrower. · Inflammation / Swelling: the ...