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An Update on the Effect of Incretin|Based Therapies on β|Cell ...


An Update on the Effect of Incretin-Based Therapies on β-Cell ...

Incretin-based therapies are now the most frequently prescribed antidiabetic drugs in Korea. Incretin-based therapies are a favorable class of drugs due to ...

(PDF) An Update on the Effect of Incretin-Based Therapies on β-Cell ...

This review outlines the current understanding of the incretin hormone system in T2DM and summarizes recent updates on the effect of incretin-based therapies on ...

[PDF] An Update on the Effect of Incretin-Based Therapies on β-Cell ...

The current understanding of the incretin hormone system in T2DM is outlined and recent updates on the effect ofincretin-based therapies on β-cell function ...

Effects of incretin-based therapies on β-cell function in type 1 ...

Based on their potential beneficial effects and promising results in animal studies, incretin-based drugs have been clinically tested in ...

The effects of incretin‐based therapies on β‐cell function and insulin ...

Conclusions. Incretin-based therapies not only show an increase in HOMA-β and fasting C-peptide level, but also achieve a reduction in HOMA-IR ...

Incretin Effects on β-Cell Function, Replication, and Mass

The recently developed diabetes therapies, GLP-1 receptor agonists, such as exenatide and liraglutide, appear to have beneficial effects on β- ...

Incretin-based therapy and pancreatic beta cells - ScienceDirect.com

In humans, incretin-based therapies are effective glucose-lowering agents, but further study is still required to evaluate their long-term effects on beta cell ...

Incretin and Pancreatic β-Cell Function in Patients with Type 2 ...

Regarding the positive effect of SGLT2 inhibitors on β-cell sensitivity to incretin hormones, the combination of incretin-based therapies and ...

An Update on the Effect of Incretin-Based Therapies on β-Cell ...

An Update on the Effect of Incretin-Based Therapies on β-Cell Function and Mass · List of references · Publications that cite this publication.

Effects of incretin-based therapies on β-cell function in type 1 ...

This meta-analysis showed that incretin-based therapies did not preserve β-cell function in patients with T1DM.

Incretin-Based Therapy and the Quest for Sustained Improvements ...

Hence, there has been considerable anticipation that incretin-based therapies may exert “disease-modifying” effects in type 2 diabetes through a ...

Incretin Therapies Do Not Expand β-Cell Mass or Alter Pancreatic ...

The impact of incretins upon pancreatic β-cell expansion remains extremely controversial. Multiple studies indicate that incretin-based ...

Effect of incretins and incretin based therapy on pancreatic β-cell in...

Antidiabetic treatments aiming to preserve, or even increase, β-cell function/mass are considered critical to long- term glucose control. Incretin-based ...

Incretin Therapies: Effects Beyond Glycemic Control - ScienceDirect

Impaired insulin secretion plays a major role in the pathogenesis of type 2 diabetes mellitus, and progressive loss of β-cell function is a pathophysiologic ...

Incretin-Based Therapies for Type 2 Diabetes Mellitus

Research on the defective incretin action in type 2 diabetes mellitus suggests that the observed loss of insulinotropic activity may be due primarily to a ...

Variation in responses to incretin therapy: Modifiable and non ...

Incretin therapy is the second line of treatment for T2D, improving both blood glucose regulation and weight loss. Glucagon-like peptide-1 (GLP- ...

Incretins-Based Therapies and Their Cardiovascular Effects - MDPI

Moreover, GLP-1RA-mediated cAMP elevation is responsible for oxidative stress reduction and trough activation of anti-apoptotic genes for pancreatic β cells ...

Incretin actions and consequences of incretin‐based therapies ...

The incretin effect comprises the phenomenon that an oral glucose load elicits higher insulin secretion compared to an isoglycaemic intravenous ...

Favorable Effects of GLP-1 Receptor Agonist against Pancreatic β ...

Incretin-based therapy substantially ameliorates glycemic control without hypoglycemia and/or weight gain, which leads one to the prevention of diabetic ...

The expanding role of incretin-based therapies: how much should ...

The incretins are peptide hormones released from the small intestine during meal absorption that stimulate insulin secretion from pancreatic β- ...