An Update on the Management of Childhood|Onset Systemic Lupus ...

An Update on the Management of Childhood-Onset Systemic Lupus ...

Childhood-onset systemic lupus erythematosus (cSLE) is a prototype of a multisystemic, inflammatory, heterogeneous autoimmune condition.

An Update on the Management of Childhood-Onset Systemic Lupus ...

Management practices for cSLE patients include evaluations of disease activity and cumulative damage scores, routine non-live vaccinations, physical activity,

An Update on the Management of Childhood-Onset Systemic Lupus ...

Anti-interferon therapies (sifalimumab and anifrolumab) have shown beneficial results in phase II randomized control trials in adult SLE patients, ...

Childhood-Onset Systemic Lupus Erythematosus - AAP Publications

Childhood-onset systemic lupus erythematosus has significant clinical variability, which can make the identification of these patients difficult ...

An Update on Treatment and Management of Pediatric Systemic ...

Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disorder in which 20 % of patients are diagnosed in childhood.

Juvenile-onset systemic lupus erythematosus: Update on clinical ...

Though less effective and potentially toxic, jSLE patients are treated based upon evidence from studies in aSLE cohorts. Here, age-specific clinical features of ...

Childhood-Onset Systemic Lupus Erythematosus: A Review and ...

About 10%-20% of all patients with SLE are diagnosed during childhood. Typically, cSLE has a more severe clinical course than that seen in adults, with a higher ...

Childhood-onset systemic lupus erythematosus: characteristics and ...

The management of cSLE is more challenging because the disease itself and treatment can affect physical, psychological and emotional growth and development.

Update οn the diagnosis and management of systemic lupus ...

For organ-threatening or life-threatening SLE, treatment usually includes an initial period of high-intensity immunosuppressive therapy to control disease ...

Revisiting Childhood-Onset Systemic Lupus Erythematosus

Disease management is complex including the control of disease activity, the reduction of flares and damage, and a limitation of drug toxicity ...

Childhood-Onset Systemic Lupus Erythematosus

60,76,78 Disease damage, in con- trast, refers to irreversible degenerative tissue and organ changes from disease activity or SLE treatment. The ...

Childhood-Onset Systemic Lupus Erythematosus (cSLE)

Childhood-onset systemic lupus erythematosus (cSLE) is a severe and potentially life-threatening chronic autoimmune disease.

Childhood-onset systemic lupus erythematosus (SLE)

... UpDates · What's New · UpToDate Pathways ... (See "Systemic lupus erythematosus (SLE) in children: Treatment, complications, and prognosis".).

Remission and long-term remission of pediatric-onset systemic ...

Conclusion: This study assessed remission of pediatric-onset SLE. Up to 60.2% of patients had clinical remission after treatment, and 19% of ...

Towards development of treat to target (T2T) in childhood-onset ...

Objectives Application of 'treat-to-target' (T2T) in childhood-onset systemic lupus erythematosus (cSLE) may improve care and health outcomes.

Systemic lupus erythematosus (SLE) in children

RELATED TOPICS · Antimalarial drugs in the treatment of rheumatic disease · Arthritis and other musculoskeletal manifestations of systemic lupus ...

Pediatric Lupus (Systemic Lupus Erythmatosus)

A final note: Medicine is essential, but it's not the sum total of your child's treatment for lupus. Many kids with lupus also require physical and occupational ...

Childhood-onset systemic lupus erythematosus: a clinical update

Recognising the signs and flares of SLE in children in general practice is important, followed by its diagnosis and treatment by a rheumatologist. This article ...

Update on differences between childhood-onset and adult-onset ...

Children have a more fulminant disease onset and course than adults with SLE, resulting in two to three times higher mortality.

Juvenile-onset systemic lupus erythematosus: Update on clinical ...

Juvenile-onset systemic lupus erythematosus: Update on clinical presentation, pathophysiology and treatment options. · E. Smith, H. Lythgoe, +2 authors. C.