An introduction to multiplicity issues in clinical trials

An introduction to multiplicity issues in clinical trials: the what, why ...

In clinical trials it is not uncommon to face a multiple testing problem which can have an impact on both type I and type II error rates, ...

An introduction to multiplicity issues in clinical trials - Oxford Academic

The purpose of this article is to provide an introduction to multiple testing issues in clinical trials, and to reduce confusion around the need for ...

An introduction to multiplicity issues in clinical trials - Semantic Scholar

An introduction to multiple testing issues in clinical trials is provided, and options for carrying out multiplicity adjustments in terms of trial design ...

Points to consider on multiplicity issues in clinical trials

The issue of setting an appropriate type I error level on a submission level when this includes the need for more than one confirmatory trial is discussed in a ...

An introduction to multiplicity issues in clinical trials - Europe PMC

Abstract. In clinical trials it is not uncommon to face a multiple testing problem which can have an impact on both type I and type II error rates, leading to ...

An introduction to multiplicity issues in clinical trials

Multiplicity issues may need to be considered at the design, analysis and interpretation stages of a trial. The proportion of trial reports not adequately ...

An introduction to multiplicity issues in clinical trials - ResearchGate

The purpose of this article is to provide an introduction to multiple testing issues in clinical trials, and to reduce confusion around the need ...

Editorial: Multiplicity issues in clinical trials - Wiley Online Library

Multiplicity control at this stage helps trial sponsors avoid incorrect drug development decisions based on spurious findings from smaller trial ...

Key Multiplicity Issues in Clinical Trials I (Introduction) - YouTube

Outline This online course gives a comprehensive overview of traditional multiplicity problems with a single source of multiplicity in ...

Multiplicity in a Clinical Trial: Why is it Important?

Multiplicity is an issue that should be controlled for in clinical studies which assess the primary endpoint in more than one way.

Multiplicity issues in clinical trials - Wiley Online Library

The consequence is an increased probability of wrong decisions in the contexts of drug approval and reimbursement if the analysis strategy does not account ...

Key Multiplicity Issues in Clinical Trials (Part I): Introduction - YouTube

For more information on the software tools featured in this online training course, please visit https://medianasoft.github.io.

Guideline on multiplicity issues in clinical trials - for publication

Guideline on multiplicity issues in clinical trials. EMA/CHMP/44762/2017. Page 4/15. 2. Introduction. 94. Multiplicity of inferences is present ...

An introduction to multiplicity issues in clinical trials

Fingerprint. Dive into the research topics of 'An introduction to multiplicity issues in clinical trials: the what, why, when and how'.

Guideline on Multiplicity Issues in Clinical Trials (Trial Version)

Type I error refers to the error in which the null hypothesis is true but the test result rejects it, in the clinical trials it is an error drawing the.

Michael Harhay on X: "'An introduction to multiplicity issues in ...

'An introduction to multiplicity issues in clinical trials: the what, why, when and how' https://t.co/hzKjw3rInZ Great open access paper in ...

An introduction to multiplicity issues in clinical trials: the what ... - OUCI

Lehana Thabane. List of references. Gewandter, Reporting of primary analyses and multiplicity adjustment in recent analgesic clinical trials: ACTTION systematic ...

Multiplicity Problem in Clinical Trials and Some Statistical Approaches

In most of the clinical trial problem, researchers often face multiple testing problems that have an impact on type I and type II error rates, results in ...

Multiplicity Considerations in Clinical Trials - AUB

However, proper treatment of multiplicity issues also plays an important role in exploratory trials (e.g., dose-finding phase 2 trials) aimed at.

Key Multiplicity Issues in Clinical Trials (Part II): Introduction - YouTube

Key Multiplicity Issues in Clinical Trials (Part II): Introduction. 187 views · 2 years ago ...more. Mediana Online. 458. Subscribe.