Anakinra in pediatric acute fulminant myocarditis

Anakinra in pediatric acute fulminant myocarditis - PMC

In this pilot study, use of IL-1 receptor antagonist in the initial treatment of acute fulminant myocarditis in children seems to be associated with rapid ...

Anakinra in pediatric acute fulminant myocarditis - PubMed

In this pilot study, use of IL-1 receptor antagonist in the initial treatment of acute fulminant myocarditis in children seems to be associated with rapid ...

Anakinra in pediatric acute fulminant myocarditis - ScienceDirect.com

Acute fulminant myocarditis in children is associated with elevated mortality and morbidity with few advances in its medical management. In adults with acute ...

Anakinra in pediatric acute fulminant myocarditis - ResearchGate

Anakinra in pediatric acute fulminant myocarditis. Louise Maunier1, Ramy Charbel1, Virginie Lambert2,3 and Pierre Tissières1,4* on behalf of the CLOVIS study.

Anakinra in pediatric acute fulminant myocarditis - ProQuest

Here we report a preliminary experience of children treated with IL-1 receptor antagonist associated with rapid myocardial function recovery.

Anakinra in pediatric acute fulminant myocarditis - SUNY Cobleskill

Background Acute fulminant myocarditis in children is associated with elevated mortality and morbidity with few advances in its medical management.

(PDF) Anakinra in pediatric acute fulminant myocarditis

Treatment comprised intravenous immunoglobulin (93%), systemic steroids (84%) and acetylsalicylic acid (100%; 26/45 started with high dosages).

Recognition and Initial Management of Fulminant Myocarditis

Fulminant myocarditis (FM) is an uncommon syndrome characterized by sudden and severe diffuse cardiac inflammation often leading to death.

Anakinra in pediatric acute fulminant myocarditis - OUCI

Abstract Background Acute fulminant myocarditis in children is associated with elevated mortality and morbidity with few advances in its medical management.

Anakinra in Fulminant Myocarditis: Targeting Interleukin-1 and the ...

Viral infection of the heart results in myocardial injury. Myocarditis presents in many different ways, ranging from mild symptoms to chest pain that can mimic ...

Anakinra treats fulminant myocarditis from Neisseria meningitidis ...

Inflammation mediated by interleukin-1 (IL-1) is thought to play a role in the pathogenesis of myocarditis and HLH, and there is some evidence ...

Anakinra is safe but does not reduce complications of acute ...

While anakinra is effective in pericarditis,3,4 there are only case reports of successfully treated acute myocarditis.5,6. ARAMIS was the ...

Anakinra in pediatric acute fulminant myocarditis - EM consulte

Acute fulminant myocarditis in children is associated with elevated mortality and morbidity with few advances in its medical management.

Anakinra treatment in multisystemic inflammatory syndrome in ...

Anakinra, a recombinant interleukin (IL)-1 receptor antagonist, is a safely preferred agent in children with MAS. But, the efficacy and safety of anakinra in ...

Rationale and design of the ARAMIS trial: Anakinra versus placebo ...

Since then, anakinra has been tested successfully in a few cases of fulminant acute myocarditis [17], [18]. The drug has also been evaluated in two phase II ...

Case Report: Life-Threatening Macrophage Activation Syndrome ...

if complicated by acute fulminant myocarditis. Based on our positive ... Anakinra for myocarditis in juvenile idiopathic arthritis. Tex ...

Innate and adaptive immunity in acute myocarditis

Anakinra treats fulminant myocarditis from Neisseria ... 109. Maunier, L. ∙ Charbel, R. ∙ Lambert, V. ... Anakinra in pediatric acute fulminant myocarditis.

Acute Myocarditis and Pericarditis in Children - AAP Publications

Treatment of myocarditis depends on the clinical scenario, with supportive care being the first line. Patients with fulminant or acute ...

VA-ECMO for fulminant myocarditis in an infant with acute COVID-19 ...

Fulminant myocarditis in children was rare during the coronavirus disease 2019 pandemic, but it had the potential for high morbidity and ...

Analysis of cytokine pro les in pediatric fulminant myocarditis and ...

Acute myocarditis (AM) is an in ammatory disease of the myocardium most often caused by viral infection or autoimmune disease [1]. Some cases of ...