Anti|TNF therapy for inflammatory bowel disease in patients with ...

Overview of TNF Inhibitors for Treating Inflammatory Bowel Disease

These medications have become the mainstay in treating IBD. Guidelines discuss using TNF inhibitors alone or in combination with other agents in ...

Anti-TNF therapy and immunogenicity in inflammatory bowel diseases

There is currently no specific cure for IBD, so the goal of treatment is to induce and maintain the state of remission in patients, thus controlling the ...

Anti-TNF Therapy in Crohn's Disease - PMC - PubMed Central

Anti-TNF (tumour necrosis factor) therapy was approved for use in Crohn's disease in 1998, and has changed the paradigm of treatment, leading to improved rates ...

Tumor Necrosis Factor Inhibitors in Inflammatory Bowel Disease and ...

In 2 nationwide cohorts of IBD patients, anti-TNF therapy was associated with an increased risk of rheumatoid arthritis, psoriasis, and ...

Evaluation of anti-TNF therapeutic response in patients ... - The Lancet

Neutralizing tumour necrosis factor (TNF) antibodies have been widely used to treat inflammatory bowel disease (IBD) in the clinical ...

Fact Sheet - Crohn's & Colitis Foundation

in patients using anti-TNF medications in combination with another immunosuppressant, such as azathioprine. (Imuran®). • Liver Problems. Biologic therapies ...

Mechanism of Action of Anti-TNF Therapy in Inflammatory Bowel ...

The first description of the successful treatment of a patient with Crohn's disease with the chimeric monoclonal IgG1 anti-TNF antibody infliximab was in 1993.

Anti–Tumor Necrosis Factor Therapy and Incidence of Parkinson ...

Patients with inflammatory bowel disease exposed to antitumor necrosis factor therapy had a 78% reduction in Parkinson disease incidence rates compared with ...

Predictors of Primary Response to Biologic Treatment [Anti-TNF ...

We have schematically divided the predictive factors of efficacy for anti-TNF agents in IBD patients into three groups: i] patient-related factors; ii] disease- ...

Dosing and monitoring of tumor necrosis factor-alpha inhibitors

GRAPHICS · - Approach to patients with IBD and anti-TNF therapy · - Management of acute reactions to infliximab infusion.

Optimizing anti-TNF treatment in inflammatory bowel disease

Infliximab, the chimeric monoclonal immunoglobulin (Ig)G1 antibody to tumor necrosis factor (TNF) has changed our therapy of Crohn's disease.

Anti-TNF therapy for inflammatory bowel disease in patients with ...

Anti-TNF therapy appears safe in patients with NPC1 and is an effective treatment strategy for the management of intestinal inflammation in these patients.

Systematic review with meta‐analysis: the efficacy of a second anti ...

One-third of patients with Crohn's disease (CD) or ulcerative colitis (UC) receiving anti-TNFs do not respond to treatment, and a relevant ...

Optimization of anti-TNF therapy in patients with Inflammatory Bowel ...

After the introduction of anti-tumor necrosis factor (anti-TNF) agents, the clinical outcome of patients with Inflammatory Bowel Disease (IBD) has improved ...

Predictive biomarkers for anti-TNF alpha therapy in IBD patients

This review aims to present a comprehensive examination of predictive biomarkers for monitoring the therapeutic response to anti-TNF therapy in IBD patients.

S126 Paradoxical Inflammatory Bowel Disease Following Anti-TNF ...

In conclusion, this study evidences IBD as a rare complication of TNF-α inhibitor therapy for RA, occurring in < 1% of this patient population. Our findings ...

Controversies in the management of anti-TNF therapy in patients ...

Background Despite research, there are still controversial areas in the management of Crohn's disease (CD). · Objective To establish practical recommendations on ...

Examining clinical and genetic factors that impact response to anti ...

Approved in 1998 for use in treating Crohn's disease and subsequently in 2005 for treating ulcerative colitis, anti-tumor necrosis factor ...

Inflammatory bowel disease as a paradoxical effect of anti-TNF ...

Anti-TNF-¿ agents are used to treat various inflammatory diseases, such as IBD, UC, rheumatoid arthritis, psoriatic arthritis and AS. Specifically, the European ...

Optimizing Anti-TNF-α Therapy: Serum Levels of Infliximab and ...

It is not clear what serum levels of anti–tumor necrosis factor are associated with reduced intestinal inflammation in patients with inflammatory bowel ...