Apoptosis in Cancer Pathogenesis and Anti|cancer Therapy

Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy

This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment.

Apoptosis in cancer: from pathogenesis to treatment

Morphological hallmarks of apoptosis in the nucleus are chromatin condensation and nuclear fragmentation, which are accompanied by rounding up ...

Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy. New ...

Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms ...

Apoptosis, cancer and cancer therapy - PubMed

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to ...

Apoptosis in cancer: from pathogenesis to treatment - PubMed

The mechanism of apoptosis is complex and involves many pathways. Defects can occur at any point along these pathways, leading to malignant ...

Review Apoptosis, cancer and cancer therapy - ScienceDirect.com

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway.

Apoptosis as anticancer mechanism: function and dysfunction of its ...

Therefore, a better understanding of the apoptotic cell death signaling pathways may improve the efficacy of cancer therapy and bypass resistance. This review ...

Apoptosis in cancer | Carcinogenesis - Oxford Academic

For example, in the skin, excessive exposure to UV radiation induces apoptosis, which presumably serves to eliminate heavily damaged cells. UV radiation induces ...

Targeting apoptotic pathways for cancer therapy - JCI

Dysregulation of and resistance to cell death are hallmarks of cancer. For over three decades, the development of therapies to promote treatment ...

Impact of Complex Apoptotic Signaling Pathways on Cancer Cell ...

Cancer cells treated with anticancer drugs undergo c-Jun/AP-1–mediated apoptotic death and are involved in c-Jun N-terminal kinase activation and growth arrest- ...

Cancer and apoptosis: The apoptotic activity of plant and marine ...

4 Why apoptosis induction is mandatory for effective chemotherapy. An anti-cancer treatment mainly kills cancer cells and may or may not cause side effects to ...

Regulated cell death (RCD) in cancer: key pathways and targeted ...

Therefore, the regulation of the apoptosis signaling pathway is one of the crucial methods to improve cancer treatment. Then, we focus on ...

The Apoptosis Paradox in Cancer - MDPI

Apoptosis is also an important cellular response to cancer therapy and, indeed, induction of cell death to remove all cancer cells is the aim of the vast ...

Apoptosis in the development and treatment of cancer

For example, the tumor suppressor gene p53 induces apoptosis by transcriptionally activating the gene for PUMA, which can bind to and antagonize anti-apoptotic ...

Broad targeting of resistance to apoptosis in cancer - ScienceDirect

Apoptosis or programmed cell death is natural way of removing aged cells from the body. Most of the anti-cancer therapies trigger apoptosis induction and ...

[Retracted] Apoptosis and Molecular Targeting Therapy in Cancer

Defect in apoptosis can cause cancer or autoimmunity, while enhanced apoptosis may cause degenerative diseases. The apoptotic signals contribute ...

Insights into the Role of Defective Apoptosis in Cancer ... - IntechOpen

One form of programmed cell death (PCD) is apoptosis. Defective apoptosis is an indispensable causative factor in the development of cancer that allows ...

Apoptosis-targeted therapies for cancer - Cell Press

important roles in tumor pathogenesis, allowing neoplastic cells ... PI3K/Akt activation, and (3) anti-CD40L antibodies and CD40L adenovirus gene therapy, which ...

Apoptosis in cancer: from pathogenesis to treatment

The abundance of literature suggests that targeting apoptosis in cancer is feasible, however, many troubling questions arise with the use of new drugs or ...

Apoptosis in cancer: From pathogenesis to treatment - ResearchGate

The selective initiation of apoptosis is a process used in cancer treatment, as it stimulates cancer cells to undergo self-destruction in a ...