Apoptosis in neurodegenerative disorders

Apoptosis in neurodegenerative disorders - Nature

Overactivation of glutamate receptors can induce apoptosis by a mechanism involving calcium influx, and such 'excitotoxicity' may occur in acute ...

Apoptosis in neurodegenerative disorders - PubMed

Neuronal death underlies the symptoms of many human neurological disorders, including Alzheimer's, Parkinson's and Huntington's diseases, stroke, ...

Apoptosis and oxidative stress in neurodegenerative diseases

Apoptosis seems to play a key role in the progression of several neurologic disorders like Alzheimer's disease, Parkinson's disease, Huntington's disease, and ...

Apoptosis and its therapeutic implications in neurodegenerative ...

Apoptosis has been implicated in the pathogenesis of neurodegenerative diseases, including Parkinson disease, Alzheimer disease, Huntington disease, and ...

Molecular mechanisms of cell death in neurological diseases - Nature

Tightly orchestrated programmed cell death (PCD) signalling events occur during normal neuronal development in a spatially and temporally ...

Insights on aspects of apoptosis in neurodegenerative disorders

In this paper, a summary of the engrossment of oxidative stress, neuronal apoptosis, and mitochondrial dysfunction in neurodegenerative disorders has been ...

Apoptosis in neurodegenerative diseases: the role of mitochondria

Abstract. Nerve cell death is the central feature of the human neurodegenerative diseases. ... Nuclear DNA is relatively preserved. Recent evidence now indicates ...

Apoptosis and Caspases in Neurodegenerative Diseases

In this article, I review the causes and mechanisms of neuronal-cell death, especially as it pertains to the caspase family of proteases associated with cell ...

Insights on aspects of apoptosis in neurodegenerative disorders

In this paper, a summary of the engrossment of oxidative stress, neuronal apoptosis, and mitochondrial dysfunction in neurodegenerative ...

Neuronal Cell Death Mechanisms in Major Neurodegenerative ...

In neurodegenerative diseases, apoptosis and necrosis are believed to be the two major death pathways for neurons [19,20]. The fundamental differences between ...

Apoptosis and Caspases in Neurodegenerative Diseases

Abstract. A form of cell death called apoptosis is a prominent feature in a broad spectrum of neurodegenerative diseases, ranging from stroke to Huntington's ...

Autophagy and apoptosis dysfunction in neurodegenerative disorders

We provide a brief introduction to autophagy and apoptosis pathways focusing on the role of mitochondria and lysosomes.

Apoptosis in neurodegenerative disorders - Lippincott

We review here recent reports pertaining to the issue of apoptosis in neurodegenerative diseases. Tissue culture models, animal models and human ...

Potential of Therapeutic Small Molecules in Apoptosis Regulation in ...

Neurodegenerative disorders (NDs) include Parkinson's disease (PD), Alzheimer's disease (AD), Huntington's disease (HD), and amyotrophic lateral sclerosis ...

Mechanisms of Neurodegenerative Disorders: Part 2: Control of Cell ...

Apoptosis occurs in many pathological situations in the brain, including ischemia, Huntington disease, and AD. In the ischemic brain, apoptotic ...

Apoptosis in neurodegenerative disorders: potential for therapy by ...

Apoptotic, rather than necrotic, nerve cell death now appears as likely to underlie a number of common neurological conditions including stroke, ...

Apoptosis and its therapeutic implications in neurodegenerative ...

Apoptosis has been implicated in the pathogenesis of neurodegenerative diseases, including Parkinson disease, Alzheimer disease, Huntington disease, and ...

6. Apoptosis in Neurodegenerative Disorders - J-Stage

10) Jenner P, et al. Oxidative stress as a cause of nigral cell death in Parkinson' s disease and incidental Lewy body disease. Ann Neurol 32: S82, 1992.

Regulated cell death: discovery, features and implications for ...

In physiology, apoptosis can remove damaged or redundant cells to ensure organism homeostasis. Excessive apoptosis may be deleterious too, such ...

Apoptosis and Oxidative Stress in Neurodegenerative Diseases

Inappropriate apoptosis control is implicated in many human diseases including neurode- generative disorders such as Alzheimer's disease (AD),. Parkinson's ...