Application of Stable Isotope Based Tracer Analysis in Human Cells

The use of stable isotopes in biomedical research has attracted more and more interest from the metabolomics society. Indeed, the technology of tracer ...

Applications of stable, nonradioactive isotope tracers in in vivo ...

In human metabolic research, the most commonly used stable isotopes include hydrogen, carbon and nitrogen isotopes that can be incorporated into ...

Stable Isotope Tracer Analysis in Isolated Mitochondria from ...

Figure 4. ... Stable isotope tracer analyses of cells and isolated mitochondria from mammalian systems. (A) Mass isotopomer analyses of metabolites extracted from ...

Isotope tracing in health and disease - ScienceDirect.com

Figure 1. Applications of isotope tracers in metabolic research. (a) Isotope tracers serve as reliable internal standards for quantifying ...

Stable isotopes: their use and safety in human nutrition studies

A number of isotopes have been used frequently to assess body composition, energy expenditure, protein turnover and metabolic studies in general.

The use of stable isotopes in the study of human pathophysiology

A metabolic stable isotope tracer is a molecule labelled with one or more stable isotopes, having a different mass from the most abundant form of that ...

Isotopic Tracer Methods of Monitoring Human Carbohydrate ...

Isotopic tracers can reveal insights into the temporal nature of metabolism and track the fate of ingested substrates. A common use of ...

Applications of Stable Isotope Labeling in Metabolic Flux Analysis

Several analytical methods are employed in the detection and quantification of these isotopes in a variety of samples ranging from cellular metabolites to body ...

Exploring Human Muscle Dynamics In Vivo Using Stable Isotope ...

Then, various stable isotope tracer methodologies that enable assessment of in vivo kinetics of protein dynamics at the muscle and whole-body levels are ...

Historical and contemporary stable isotope tracer approaches to ...

Since their initial isolation and implementation in the 1930s, stable isotope tracers have provided the scientific community with great insight ...

Stable Isotopes for Tracing Mammalian-Cell Metabolism in vivo - Lirias

approaches for interpreting in vivo tracer measurements based solely on MDV analysis, allowing to obtain ... (2016) Applications of Stable, Nonradioactive Isotope ...

Laboratory and Field Methods for Stable Isotope Analysis in Human ...

Unlike experimental studies using spiked isotopic tracers, in archaeology and ecology, natural abundances of stable isotopes of carbon, nitrogen ...

Stable Isotopes for Tracing Mammalian-Cell Metabolism In Vivo

Metabolic models integrating stable-isotope tracer measurements in tissues and plasma allow quantitative readouts of in vivo metabolism at the ...

Stable Isotope Tracers for Metabolic Pathway Analysis

Stable isotope tracing allows a metabolic substrate to be followed through downstream biochemical reactions, thereby providing unparalleled insights into ...

Stable isotope usage in developing countries: Safe tracer tools to ...

An inventory of the human body shows that a 50-kilogram individual has an aggregate of 225 grams of hydrogen-2, carbon-13, nitrogen-15, oxygen-17, and oxygen-18 ...

Tracing lipid metabolism: the value of stable isotopes in

Labelling molecules with stable isotopes to create tracers has become a gold-standard method to study the metabolism of lipids and lipoproteins in humans.

Stable Isotopes - Sigma-Aldrich

Both tracer and flux studies benefit from stable isotope label assistance. Metabolic pathways can be studied by tracking naturally-occurring and disease- ...

Stable isotope tracers: Enriching our perspectives and questions on ...

Stable isotope applications have evolved from simple characterizations of isotope composition in organisms and organic matter, ...

[PDF] Applications of stable, nonradioactive isotope tracers in in vivo ...

Basic principles of stable isotope methodology for tracing in vivo kinetics of human or animal metabolism are introduced with examples of quantifying ...

Application of enriched stable isotopes as tracers in biological systems

PDF | The application of enriched stable isotopes of minerals and trace elements as tracers in biological systems is a rapidly growing research field.