Arf GTPase activates the WAVE regulatory complex through a ...

Cross-talk between Rho- and Arf-family guanosine triphosphatases (GTPases) plays an important role in linking the actin cytoskeleton to ...

Arf GTPase activates the WAVE Regulatory Complex through a ...

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Arf GTPase activates the WAVE regulatory complex ... - NASA ADS

Cross-talk between Rho- and Arf-family guanosine triphosphatases (GTPases) plays an important role in linking the actin cytoskeleton to membrane protrusions ...

Arf GTPase activates the WAVE Regulatory Complex through a ...

The central actin regulator, WAVE Regulatory Complex (WRC), is a converging point of Rac1 (a Rho-family GTPase) and Arf signaling in many ...

WAVE regulatory complex activation by cooperating GTPases Arf ...

Our findings suggest that Arf GTPases may be central components in WAVE signalling, acting directly, alongside Rac1.

(PDF) Arf GTPase activates the WAVE Regulatory Complex through ...

The central actin regulator, WAVE Regulatory Complex (WRC), is a converging point of Rac1 (a Rho-family GTPase) and Arf signaling in many ...

(PDF) Arf GTPase activates the WAVE regulatory complex through a ...

The central actin regulator, WAVE regulatory complex (WRC), integrates Rac1 (a Rho-family GTPase) and Arf signaling to promote Arp2/3-mediated ...

WAVE regulatory complex activation by cooperating GTPases Arf ...

By reconstituting WAVE-dependent actin assembly on membrane-coated beads in mammalian cell extracts, it is found that Rac1 was not sufficient to engender ...

Arf GTPase activates the WAVE Regulatory Complex through ... - OUCI

SummaryCrosstalk between Rho- and Arf-family GTPases plays an important role in linking actin cytoskeletal remodeling to membrane protrusion, ...

(PDF) Arf GTPase activates the WAVE Regulatory Complex through ...

Rho-family GTPase Rac1 activates the WAVE regulatory complex (WRC) to drive Arp2/3-mediated actin polymerization in many essential processes.

Structures reveal a key mechanism of WAVE regulatory complex ...

The Rho-family GTPase Rac1 activates the WAVE regulatory complex (WRC) to drive Arp2/3 complex-mediated actin polymerization in many essential processes.

Rac1 GTPase activates the WAVE regulatory complex through two ...

The Rho GTPase Rac1 activates the WAVE regulatory complex (WRC) to drive Arp2/3 complex-mediated actin polymerization, which underpins diverse cellular ...

Arf GTPase interplay with Rho GTPases in regulation of the actin ...

This review highlights how Arf GTPases collaborate with Rac1 to regulate actin cytoskeleton dynamics at the membrane via recruiting and activating the Wave ...

Orchestration of synaptic functions by WAVE regulatory complex ...

The WRC is intrinsically inactive but is activated upon interaction with numerous cytosolic proteins, small GTPases, and transmembrane receptors ...

WAVE regulatory complex: Current Biology - Cell Press

Aside from Rac1, other GTPases have also been suggested to play a role in WRC activation, such as the Arf-family GTPases Arf1 and Arf6, or tune ...

WAVE Regulatory Complex Activation - ScienceDirect.com

We identified an unexpected role for Arf family GTPases, which synergize with Rac1 to efficiently recruit WRC to the membrane and trigger WAVE-dependent actin ...

The WAVE Regulatory Complex Links Diverse Receptors to the ...

WAVE regulatory complex activation by cooperating GTPases Arf and Rac1. Proc ... GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.

Arf6 Can Trigger Wave Regulatory Complex-Dependent Actin ...

Like other GTPases, Arf GTPases are also under tight spatial and temporal regulation by their guanine nucleotide-exchange factors (GEFs) and GTPase-activating ...

Arf GTPase activates the WAVE regulatory complex ... - Biofactoid

Sra1 binds with Rac1. Rac1 activates Sra1 via binding. Arf1 activates Sra1 via binding. : Arf GTPase activates the WAVE regulatory complex through a ...

Inhibition of WAVE Regulatory Complex Activation by a Bacterial ...

The phosphoinositide PIP3 is known to activate the WRC through Rac1 and Arf GTPases (Lebensohn and Kirschner, 2009, Koronakis et al., 2011), and ...