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Article A Novel Cofactor for p300 that Regulates the p53 Response


A novel cofactor for p300 that regulates the p53 response - PubMed

We report a novel cofactor for p300 that facilitates the p53 response by augmenting p53-dependent transcription and apoptosis. JMY and p300 associate in ...

Article A Novel Cofactor for p300 that Regulates the p53 Response

Abstract. The ability of p53 to function as a transcription factor is instrumental in facilitating the response to cellular stress, and p300/CBP proteins, which ...

A Novel Cofactor for p300 that Regulates the p53 Response

The ability of p53 to function as a transcription factor is instrumental in facilitating the response to cellular stress, and p300/CBP proteins, ...

A Novel Cofactor for p300 that Regulates the p53 Response

We report a novel cofactor for p300 that facilitates the p53 response by augmenting p53-dependent transcription and apoptosis. JMY and p300 associate in ...

A TPR Motif Cofactor Contributes to p300 Activity in the p53 Response

The transcription of p53 target genes involves p300/CBP coactivators, which are multiprotein complexes that interact with the p53 activation domain.

Negative regulation of the p300-p53 interplay by DDX24 - PMC - NCBI

Numerous studies indicate that p300 acts as a key transcriptional cofactor in vivo, at least, in part, through modulating activities of p53 ...

A novel cofactor for p300 that regulates the p53 response. | BioGRID

The Ability Of P53 To Function As A Transcription Factor Is Instrumental In Facilitating The Response To Cellular Stress, And P300/CBP Proteins, ...

The p53 cofactor Strap exhibits an unexpected TPR motif ... - PNAS

N Shikama, et al., A novel cofactor for p300 that regulates the p53 response. ... Purchase this article to access the full text. Single Article Purchase. The p53 ...

A Novel Cofactor for p300 that Regulates the p53 Response | CoLab

The ability of p53 to function as a transcription factor is instrumental in facilitating the response to cellular stress, and p300/CBP proteins, ...

Review Regulation and function of the p53 tumor suppressor protein

Article preview. Abstract; Introduction; Section snippets ... N Shikama et al. A novel cofactor for p300 that regulates the p53 response ...

A transcription co-factor integrates cell adhesion and motility ... - PNAS

References · 1. E Sahai, Illuminating the metastatic process. · 2. N Shikama, et al., A novel cofactor for p300 that regulates the p53 response. · 3. C Demonacos, ...

The Role of JMY in p53 Regulation - MDPI

2.4. JMY Increases p53 Dependent Transcription Leading to Selective Increase in Apoptosis · Higher levels of p300/JMY increase p53 transcriptional activity ...

Heat shock factor-1 modulates p53 activity in the transcriptional ...

Journal Article. Heat shock factor-1 modulates p53 activity ... A novel cofactor for p300 that regulates the p53 response. ,. Mol. Cell. ,. 1999.

Novel link between E2F and p53: proapoptotic cofactors of ... - Nature

JMY, another proapoptotic cofactor of p53, interacts with p300, which functions as a coactivator for p53, thereby enhancing the ability of p53 ...

p300/CBP/p53 interaction and regulation of the p53 response - 2001

Through physical interaction with p53, p300/CBP can both positively and negatively regulate p53 transactivation, as well as p53 protein turnover ...

Characterization of genome-wide p53-binding sites upon stress ...

Journal Article. Characterization of genome-wide p53-binding sites upon stress ... A novel cofactor for p300 that regulates the p53 response. ,. Mol. Cell ...

p53-family proteins and their regulators: hubs and spokes in tumor ...

Nat Rev Cancer 2009; 9: 749–758. Article CAS PubMed PubMed Central Google Scholar ... A novel cofactor for p300 that regulates the p53 response.

Strap: A versatile transcription co-factor

http://www.landesbioscience.com/journals/cc/article/6480. Extra ... A novel cofactor for p300 that regulates the p53 response. Mol Cell ...

Runt-related Transcription Factor 1 (RUNX1) Stimulates Tumor ...

A novel cofactor for p300 that regulates the p53 response. Mol. Cell. 1999; 4 ... Article metrics. 49. Citations. 50. Captures. Plum X logo. View details. Related ...

Arginine methylation regulates the p53 response. - Abstract

We show that the protein arginine methyltransferase (PRMT) 5, as a co-factor in a DNA damage responsive co-activator complex that interacts with p53, is ...