Assess statin|associated myalgia on a patient|by|patient basis

Assess statin-associated myalgia on a patient-by-patient basis

Becker said. “Some physicians suggest that true myalgia is only present if muscle pain or cramping has occurred on multiple statins, and improves after each ...

Statin-Associated Myopathy: Emphasis on Mechanisms and ...

Despite the statin-therapy-mediated positive effects on cardiovascular events, patient compliance is often poor. Statin-associated muscle symptoms (SAMS) are ...

Clinical Algorithm for Diagnosis and Management of Myalgia

Data from systematic reviews, meta-analyses, clinical and observational trials, and postmarketing surveillance indicate that statin-associated myalgia typically ...

Investigating myalgia in patients taking statins - bpac NZ

It is recommended that once a patient is initiated on statin treatment that their lipid profile should be monitored every three to six months, ...

Statin-associated muscle symptoms: impact on statin therapy ...

One study showed muscle injury in 25 of 44 patients with myopathy and in one patient taking statin without myopathy, whereas another study ...

Outcomes in 45 Patients With Statin-Associated Myopathy | Cardiology

02) but were similar in other patient characteristics (data not shown). In hospitalized patients, the duration of statin therapy before the onset of muscle pain ...

CLINICAL REVIEW Statin induced myopathy - The BMJ

When a patient taking statins reports muscle pain or weakness, a detailed history should be taken to assess predisposition to myopathy, and a physical examina-.

Statin Safety and Associated Adverse Events: A Scientific Statement ...

Discontinuation of the statin in a patient with statin-induced myopathy is typically followed by a falling CK and resolution of symptoms, but ...

An assessment by the Statin Muscle Safety Task Force: 2014 update

Studies to date indicate that symptoms of myalgia are more likely to occur within the first month of treatment. For example, in STOMP, time to symptom onset was ...

Statin-Associated Side Effects - JACC Journals

Clinically important muscle symptoms, including rhabdomyolysis and statin-induced necrotizing autoimmune myopathy (SINAM), are rare. Antibodies against HMG-CoA ...

Provider recommendations for patient-reported muscle symptoms on ...

Of the respondents, 60% of former statin users (n = 1220) reported ever experiencing new or worsened muscle pain on a statin, in contrast to 25% of current ...

Effect of statin therapy on muscle symptoms - The Lancet

These results from randomised double-blind trials suggest that when a patient reports muscle symptoms when taking a statin, the probability that it is actually ...

Statin associated muscle symptoms (SAMS): strategies for ...

Molecular basis of statin-associated myopathy. Atherosclerosis. 2009;202 ... N-of-1 (single-patient) trials for statin-related myalgia. Ann Intern Med ...

Reinitiation of Statins After Statin-Associated Musculoskeletal ...

Statins aimed at improving the cardiovascular risk of our patient caused musculoskeletal side effects that reduced the quality of life of our ...

Mechanisms and assessment of statin‐related muscular adverse ...

Several patient-related risk factors of statin-associated myopathy have been identified (Table 3). An increase of creatine kinase (CK) serum ...

Molecular basis of statin-associated myopathy

understanding of the molecular mechanisms involved in statin-induced myopathy may help identify patient groups susceptible to statins' side effects, thereby ...

Statin-Associated Muscle Symptoms Among New Statin Users ...

Muscle pain is common in the general population, so it is not surprising that these symptoms are also common among patients treated with statins ...

That Myalgia of Yours Is Not From Statin Intolerance - JACC Journals

Among participants asked about SAMS, there is no difference between statin- and placebo-treated groups. In statin trials that did not actively ...

series of randomised, placebo controlled n-of-1 trials - The BMJ

For a patient in routine clinical care, reliably determining whether muscle symptoms are caused by statins is not easy for the clinician or ...

Pathophysiological mechanisms of statin‐associated myopathies ...

Myopathy occurs with an incidence of 195 cases per 100 000 patient-years (frequency <0.1% in patients on monotherapy with statins). Lastly, in ...