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Assessing the quality of case|control association studies on the ...


Assessing the quality of case-control association studies on the ...

Once the gene of interest and polymorphisms to be studied are established, an investigator must decide what type of genetic association study to perform. For ...

Assessing the quality of case-control association studies ... - PubMed

Case-control candidate gene association studies represent an important tool for understanding the role that genes play in the pathogenesis of sepsis.

Data quality control in genetic case-control association studies

This protocol details the steps for data quality assessment and control that are typically carried out during case-control association ...

Systematic Reviews: Step 6: Assess Quality of Included Studies

Quality Assessment tools are questionnaires created to help you assess the quality of a variety of study designs. Depending on the types of studies you are ...

Assessing the quality of published genetic association studies in ...

This tool can be used in systematic reviews to inform the selection of studies for inclusion, to conduct sensitivity analyses, and to perform meta-regressions.

Study Design 101: Case Control Study - Research Guides

Case control studies are observational because no intervention is attempted and no attempt is made to alter the course of the disease. The goal ...

Systematic Review Toolbox: Quality Assessment - JABSOM Library

Assessing the quality of evidence contained within a systematic review is as important as analyzing the data within.

Data quality control in genetic case-control association studies. - ORA

This protocol details the steps for data quality assessment and control that are typically carried out during case-control association studies.

Tools for assessing quality and susceptibility to bias in observational ...

Background Assessing quality and susceptibility to bias is essential when interpreting primary research and conducting systematic reviews and meta-analyses.

Data quality control in genetic case-control association studies

This protocol details the steps for data quality assessment and control that are typically carried out during case-control association studies.

Case-Control Study - an overview | ScienceDirect Topics

Association between exposure and outcome in case-control studies is quantified using the odds ratio, which for rare diseases is a reasonable estimate of the ...

(PDF) Data quality control in genetic case-control association studies

This protocol details the steps for data quality assessment and control that are typically carried out during case-control association studies.

Assessing the performance of genome-wide association studies for ...

Detailed AUROC comparisons indicate that most SNP-derived risk predictions are not as good as clinically based disease risk predictors. All our calculations ( ...

A tutorial on conducting genome‐wide association studies: Quality ...

... association studies: Quality control and statistical analysis. Andries ... Data quality control in genetic case-control association studies.

Genome-wide association studies | Nature Reviews Methods Primers

... quality control analysis and other stages of GWAS are summarized in Table 1). ... A common GWAS design is a case–control study, in which ...

Genomewide Association Studies and Assessment of the Risk of ...

Rapid advances in technology and quality control now permit affordable, reliable genotyping of up to 1 million SNPs in a single scan of a ...

Evaluating the Clinical Validity of Gene-Disease Associations

Each study categorized as “case-control data” should be independently assessed to evaluate the quality of the study design (see Figure 2). Consultation with a ...

Methodological quality assessment of genetic studies on brain ...

Six case-control studies and three cohort studies were identified ... Assessing the quality of published genetic association studies in ...

On Quality Control Measures in Genome-Wide Association Studies

Allele transmissions in pedigrees provide a natural way of evaluating the genotyping quality of a particular proband in a family-based, genome-wide ...

Case-control and cohort studies in the age of genome-wide ...

Assessing associations in case-control and cohort studies. Source: Reprinted ... Assessment of genotyping quality may be particularly important in case-control ...