Association Between Circulating Tumor DNA and Survival in ...

Circulating Tumor DNA and Survival in Metastatic Breast Cancer

Aggregated analysis revealed a significant association between ctDNA detection and worse survival (hazard ratio, 1.40; 95% CI, 1.22-1.58).

Association Between Circulating Tumor DNA and ... - PubMed

Importance: Longitudinal circulating tumor DNA (ctDNA) has been shown to predict response and survival in patients with metastatic melanoma ...

Circulating Tumor DNA Is Associated with Response and Survival in ...

Our results demonstrate that detection of ctDNA is associated with outcome and objective response to chemotherapy in patients with advanced LMS. These results ...

ctDNA-based molecular residual disease and survival in resectable ...

The interim analysis of the CIRCULATE-Japan GALAXY observational study demonstrated the association of circulating tumor DNA (ctDNA)-based ...

Association between circulating tumor DNA (ctDNA) and recurrence ...

No significant differences in demographics, including stage, number of + lymph nodes, and BRAF status, existed between pts who were ctDNA+ or ...

Association of circulating tumor DNA with patient prognosis in ...

Detection of plasma ctDNA using a personalized assay is prognostic of recurrence in patients with resected RCC.

A longitudinal circulating tumor DNA-based model associated with ...

One of the great challenges in therapeutic oncology is determining who might achieve survival benefits from a particular therapy.

Circulating DNA and Survival in Solid Tumors - AACR Journals

Sixteen studies reported univariable data for OS at 3 years. Pooled results showed that expression of ctDNA was associated with ...

Association Between Circulating Tumor DNA and Recurrence-Free ...

Association Between Circulating Tumor DNA and Recurrence-Free Survival in Patients with Resected Stage III Melanoma · Fill form to unlock content.

Association of Circulating Tumor DNA and ... - JAMA Network

Patients had blood samples collected for ctDNA and CTCs at time of treatment assignment; ctDNA analysis with survival was performed for 142 ...

Changes in circulating tumor DNA and outcomes in solid tumors ...

The utilization of a systematic review provides an increased level of certainty regarding the association between ctDNA reduction and improved outcomes. This ...

Association Between Circulating Tumor DNA and Survival in ...

The detection of ctDNA was significantly associated with worse survival outcomes (overall survival HR, 1.44; progression-free survival HR, 1.31; ...

Survival Implications of the Relationship between Tissue versus ...

Interrogating the genomics of circulating tumor DNA (ctDNA; the liquid biopsy) has advantages in patients in whom tissue biopsy is difficult.

Changes in Circulating Tumor DNA Reflect Clinical Benefit Across ...

We observed strong associations between reductions in ctDNA levels from on-treatment liquid biopsies with improved OS (OS; hazard ratio, 2.28; ...

Analysis of Circulating Tumor DNA Predicts Outcomes of Short ...

Detection of ctDNA predicted significantly inferior progression-free survival after completion of CRT (24-mo 29% versus 65%, p = 0.0048), before C2D1 of CPI (24 ...

Circulating tumor DNA in neoadjuvant-treated breast cancer reflects ...

At baseline (T0), ctDNA-positive patients had increased risk of metastatic recurrence, but this association did not reach statistical significance (HR 4.11; 95% ...

Association of personalized and tumor-informed ctDNA with patient ...

Positive ctDNA detection was found to be significantly associated with shorter disease-free survival within the MRD window and during the ...

Circulating tumor DNA clearance predicts prognosis across ...

Circulating tumor DNA (ctDNA), validated as a tool for mutation detection in lung cancer, could reflect dynamic molecular changes. We evaluated the utility of ...

Evidence for the Utility of ctDNA Monitoring for Recurrence After

In the present analysis, ctDNA positivity emerged as the most significant prognostic factor associated with poor OS, outperforming other well ...

Regulatory implications of ctDNA in immuno-oncology for solid tumors

In the era of precision oncology, use of circulating tumor DNA (ctDNA) is emerging as a minimally invasive approach for the diagnosis and ...