Association of circulating tumor DNA with patient prognosis in ...

Detection of plasma ctDNA using a personalized assay is prognostic of recurrence in patients with resected RCC.

The median follow-up was 62 months. RESULTS: Plasma ctDNA was detected in 18 out of 36 patients (50%) pre-operatively and was associated with ...

Association between plasma circulating tumor DNA and the ...

Our results indicate plasma ctDNA may serve as robust prognostic markers for OS, DFS/RFS, and PFS among EC patients.

Circulating Tumor DNA Predicts the Response and Prognosis in ...

Positive baseline ctDNA was detected in 21 of 44 patients before NAC. Most patients with positive ctDNA had one or more mutations confirmed in ...

Circulating Tumor DNA and Survival in Metastatic Breast Cancer

Findings In this systematic review and meta-analysis reporting data from 4264 patients in 37 studies, detection of ctDNA was associated with ...

Association of personalized and tumor-informed ctDNA with patient ...

Positive ctDNA detection was found to be significantly associated with shorter disease-free survival within the MRD window and during the ...

A longitudinal circulating tumor DNA-based model associated with ...

The relatively higher ctDNA levels in patients with metastatic cancer compared to early-stage disease suggest this setting would be well suited ...

Association of Tumor-informed Circulating Tumor DNA Detectability ...

ctDNA testing in patients with bladder cancer undergoing RC was prognostic and potentially predictive. Identification of patients at high risk ...

Association of Circulating Tumor DNA and ... - JAMA Network

Patients had blood samples collected for ctDNA and CTCs at time of treatment assignment; ctDNA analysis with survival was performed for 142 ...

Association of circulating tumor DNA dynamics with clinical ...

Background: Circulating tumor DNA (ctDNA)-based molecular residual disease (MRD) has the potential to select patients who may benefit more ...

Prognostic and Predictive Impact of Circulating Tumor DNA in ...

A “molecular response” metric identified long-term responders and adjudicated benefit among patients with initially radiologically stable disease. Changes in ...

ctDNA-based molecular residual disease and survival in resectable ...

The significantly shorter DFS in MRD-positive patients was consistent across actionable biomarker subsets. Sustained ctDNA clearance in response ...

Prognostic value of plasma circulating tumor DNA fraction across ...

Genomic analysis of circulating tumor DNA (ctDNA) is increasingly incorporated into the clinical management of patients with advanced cancer ...

Association of preoperative and postoperative circulating tumour ...

Recently, researchers have identified the feasibility of detecting PIK3CA gene mutations in ctDNA in patients with early-stage breast cancer in preop period and ...

Circulating DNA and Survival in Solid Tumors - AACR Journals

Methods: A systematic review of electronic databases identified publications exploring the association between cfDNA or ctDNA and overall survival (OS) in solid ...

Association of circulating tumor DNA with patient prognosis in ...

046; HR = 3.23, P = .003, respectively). Among patients who were ctDNA positive at any time point, the sensitivity of relapse prediction was 84% ...

Diagnostic and prognostic value of circulating tumor DNA in gastric ...

Background: Circulating tumor DNA (ctDNA) has offered a minimally invasive approach for detection and measurement of gastric cancer (GC).

Regulatory implications of ctDNA in immuno-oncology for solid tumors

Circulating tumor DNA (ctDNA) is an increasingly important biomarker being developed for the diagnosis and management of patients with cancer ...

Circulating Tumor DNA Analysis in Patients With Cancer - Allen Press

All ctDNA assays have an appreciable rate of discordance with tumor testing, and the ctDNA assay may not detect the variant observed in the ...

"Association of Circulating Tumor DNA Testing Before Tissue ...

CONCLUSIONS AND RELEVANCE: This nonrandomized clinical trial found that the use of plasma ctDNA genotyping before tissue diagnosis among ...