Associations of Combined Genetic and Lifestyle Risks With Incident ...

In this population-based cohort study of 339 003 individuals, health behaviors were associated with incident cardiovascular disease and diabetes within and ...

In this large contemporary population, genetic composition and combined health behaviors and factors had a log-additive effect on the risk ...

Associations of Combined Genetic and Lifestyle Risks With Incident ...

In this population-based cohort study of 339 003 individuals, health behaviors were associated with incident cardiovascular disease and diabetes within and ...

Associations of Combined Genetic and Lifestyle Risks With Incident ...

A lifestyle which includes no smoking, moderate to high levels of physical activity, a healthy diet and BMI less than 25 is associated with a vastly reduced ...

Associations of combined genetic and lifestyle risks with ... - Nature

No study, to our knowledge, has constructed a polygenic risk score based on clinical blood pressure and investigated the association of ...

275-OR: Associations of Combined Genetic and Lifestyle Risks with ...

Overall, high genetic risk and poor lifestyle were the strongest risk factors for incident T2D. Individuals at all levels of genetic risk ...

Associations of combined lifestyle and genetic risks with incident ...

There was no interaction between genetic risk and lifestyle. The population attributable fractions of lifestyle and genetic risk were 32.2% (95% CI, 25.1%-38.6 ...

Associations of Combined Genetic and Lifestyle Risks With Incident ...

In this large contemporary population, genetic composition and combined health behaviors and factors had a log-additive effect on the risk of developing ...

Associations of combined lifestyle and genetic risks with incident ...

Conclusion. The favorable lifestyle was associated with a lower psoriasis risk among participants with each level of genetic risk. Lifestyle factors are ...

Association of genetic risk, lifestyle, and their interaction with obesity ...

We observed significant interaction between high genetic risk and poor lifestyles (pinteraction < 0.001). Absolute differences in obesity risk ...

Association of Joint Genetic and Social Environmental Risks With ...

We present the absolute risk of incident MI for 8 years among White participants for each combination of genetic and social environmental risks ...

Associations of combined phenotypic aging and genetic risk ... - eLife

The overall incident cancer risk is associated with both genetic risk and PhenoAgeAccel in a dose-response manner (Figure 4). Of participants ...

Associations of genetic susceptibility and healthy lifestyle with ...

A favourable lifestyle at high genetic risk had lower 12-year absolute risk of CHD and stroke, compared with an unfavourable lifestyle at low-to-intermediate ...

Interaction of genetic risk and lifestyle on the incidence of atrial ...

There was a positive interaction on an additive scale between genetic risk and lifestyle. The interaction indicates that adherence to a healthy lifestyle is ...

Association of Lifestyle With Incidence of Heart Failure According to ...

Combined lifestyle was associated with incident HF regardless of metabolic or genetic risk status, supporting the recommendation of healthy lifestyles for HF ...

Genetic risk, incident stroke, and the benefits of adhering ... - The BMJ

A high genetic risk combined with an unfavourable lifestyle profile was associated with a more than twofold increased risk of stroke compared ...

Synergistic effect of genetic predisposition and lifestyle for coronary ...

Joint association of combined lifestyle and polygenic risk score with incident coronary heart disease. Joint. Figure 1. Joint association of ...

Associations between polygenic risk of coronary artery disease and ...

In all genetic risk groups, adherence to a favorable lifestyle was associated with a reduced risk of CV mortality. In groups with very high genetic risk for CAD ...

Modifiable Lifestyle Factors, Genetic Risk, and Incident Peripheral ...

To prospectively evaluate the association between modifiable lifestyle factors and peripheral artery disease (PAD) among individuals with type 2 diabetes (T2D).

Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

The relative risk of incident coronary events was 91% higher among participants at high genetic risk (top quintile of polygenic scores) than ...