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Associations of combined phenotypic aging and genetic risk ...


Associations of combined phenotypic aging and genetic risk with ...

We explored a new measure of aging-Phenotypic Age (PhenoAge)-in the risk prediction of site-specific and overall cancer.

Associations of combined phenotypic ageing and genetic risk with ...

PhenoAgeAccel was significantly associated with incident risk of common chronic respiratory diseases and decreased lung function and could serve as a novel ...

Associations of Combined Phenotypic Aging and Genetic Risk with ...

In summary, our study showed that accelerated aging, which was measured by PhenoAgeAccel, was consistently related to an increased risk of ...

Associations of combined phenotypic aging and genetic risk ... - eLife

This article presents compelling results that show Phenotypic Age Acceleration (PhenoAgeAccel) can predict cancer incidence of different types.

Associations of combined phenotypic ageing and genetic risk with ...

Background. Accelerated biological ageing has been associated with an increased risk of several chronic respiratory diseases. However, the associations between ...

Associations of Combined Phenotypic Aging and Genetic Risk with ...

Conclusions Within and across genetic risk groups, older PhenoAge was consistently related to an increased risk of incident cancer with ...

Associations of combined phenotypic ageing and genetic risk with ...

Background Accelerated biological ageing has been associated with an increased risk of several chronic respiratory diseases. However, the associations ...

Associations of Combined Phenotypic Aging and Genetic Risk with ...

Associations of Combined Phenotypic Aging and Genetic Risk with Incident. 1. Cancer: A Prospective Cohort Study. 2. 3. Lijun Bian1,2†, Zhimin ...

Associations of combined accelerated biological aging and genetic ...

Accelerated biological aging has been verified to be a critical risk factor for a number of age-related diseases, but its role in dementia ...

Associations of combined phenotypic ageing and genetic risk with ...

Joint effects of phenotypic age acceleration (PhenoAgeAccel) and polygenic risk score (PRS) on the risk of chronic respiratory diseases. a) idiopathic pulmonary ...

Associations of combined phenotypic aging and genetic risk with ...

Conclusions Within and across genetic risk groups, older PhenoAge was consistently related to an increased risk of incident cancer with ...

Associations of Combined Phenotypic Aging and Genetic Risk with ...

Age is the most important risk factor for cancer, but aging rates are heterogeneous across individuals. We explored a new measure of aging-Phenotypic Age ...

Associations of Combined Phenotypic Aging and Genetic Risk with ...

Download Citation | Associations of Combined Phenotypic Aging and Genetic Risk with Incident Cancer: A Prospective Cohort Study | Age is the most important ...

Associations between biological ageing and the risk of, genetic ...

Among participants with high genetic predisposition to rheumatoid arthritis, accelerated biological ageing was associated with an increased risk ...

Associations of genetics, behaviors, and life course circumstances ...

We recently developed and validated a novel multi-system-based aging measure, Phenotypic Age (PhenoAge), which has been shown to capture ...

Association of phenotypic age and accelerated aging with severity ...

Chronological age has been considered as the strongest risk factor for aging-related death and disease [20,32]. However, individuals with the same chronological ...

Genetic links between ovarian ageing, cancer risk and de ... - Nature

The SAMHD1 association reinforces the link between ovarian ageing and cancer susceptibility, with damaging germline variants being associated ...

Improving Phenotypic Prediction by Combining Genetic ... - Cell Press

The differential effects of the BMI methylation profiles by age support previous observations of age modulation of genetic contributions. In contrast, ...

Genetic associations for two biological age measures point to ...

Biological age measures outperform chronological age in predicting various aging outcomes, yet little is known regarding genetic predisposition.

Genetic and phenotypic analysis of the causal relationship between ...

We consider four lifespan-related traits (parental lifespan, healthspan, longevity, and healthy aging (the combination of these three traits)) ...