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Autocrine VEGF Signaling Is Required for Vascular Homeostasis


Autocrine VEGF signaling is required for vascular homeostasis

Vascular endothelial growth factor (VEGF) is essential for developmental and pathological angiogenesis. Here we show that in the absence of ...

Autocrine VEGF Signaling Is Required for Vascular Homeostasis

Summary. Vascular endothelial growth factor (VEGF) is essential for developmental and pathological angiogenesis. Here we show that in the ...

Autocrine VEGF signaling is required for vascular homeostasis - PMC

Here we showed that in the absence of any pathological insult, autocrine VEGF is required for the homeostasis of blood vessels in the adult.

Autocrine VEGF Signaling Is Required for Vascular Homeostasis

These results reveal a cell-autonomous. VEGF signaling pathway that holds significance for vascular homeostasis but is dispensable for the angiogenic cascade.

Autocrine VEGF maintains endothelial survival through regulation of ...

Our data suggest that endothelial VEGF maintains vascular homeostasis through regulation of FOXO1 levels, thereby ensuring physiological metabolism and ...

Supplemental Data Autocrine VEGF Signaling Is Required for ...

Autocrine VEGF Signaling Is Required for Vascular Homeostasis. Sunyoung Lee, Tom T. Chen, Chad L. Barber, Maria C. Jordan, Jared Murdock, Sharina. Desai ...

Autocrine VEGF Signaling Is Required for Vascular Homeostasis

Request PDF | Autocrine VEGF Signaling Is Required for Vascular Homeostasis | Vascular endothelial growth factor (VEGF) is essential for developmental and ...

Autocrine VEGF Signaling Is Required for Vascular Homeostasis

Vascular endothelial growth factor (VEGF) is essential for developmental and pathological angiogenesis. Here we show that in the absence of any pathological ...

Autocrine VEGF Signaling Is Required for Vascular Homeostasis

Autocrine VEGF Signaling Is Required for Vascular Homeostasis · Cell, August 2007 · 10.1016/j.cell.2007.06.054 · 17719546 · Sunyoung Lee, Tom T. Chen, Chad L.

Autocrine VEGF Isoforms Differentially Regulate Endothelial Cell ...

Vascular endothelial growth factor A (VEGF) is involved in all the essential biology of endothelial cells, from proliferation to vessel function, ...

Endogenous Vascular Endothelial Growth Factor-A (VEGF-A ...

vivo (20), and autocrine VEGF-A was shown to be required for ... crine VEGF signaling is required for vascular homeostasis. Cell 130 ...

Autocrine VEGF maintains endothelial survival through regulation of ...

discern between the need of VEGF in vascular homeostasis from its ... Autocrine VEGF · signaling is required for vascular homeostasis. Cell 130, 691 ...

Autocrine activity of soluble Flt-1 controls endothelial cell function ...

Recently it was shown that autocrine VEGF signaling is required for vascular homeostasis [25]. Here we demonstrate that endothelial sFlt-1 expression is ...

Vascular Endothelial Growth Factor: Much More than an ...

Such autocrine-VEGF signaling in endothelial cells appeared to be entirely intracellular because only cell-permeable VEGF receptor antagonists, ...

Autocrine VEGF-B signaling maintains lipid synthesis and ... - JCI

Autocrine VEGF-B is required for lipid synthesis in activated T cells. (A and B) RNA-Seq of TCR-stimulated CD4+ T cells treated with αVB or IgG; ...

The VEGF Family, the Inside Story - ScienceDirect.com

The role of paracrine signaling by vascular endothelial growth factor (VEGF) in the formation and maintenance of blood vessels has been ...

VEGF-dependent tumor angiogenesis requires inverse and ... - Nature

Vascular endothelial growth factor (VEGF) signaling is critical for tumor angiogenesis. However, therapies based on inhibition of VEGF ...

Endogenous Vascular Endothelial Growth Factor-A (VEGF-A ...

We found that it is complexed with VEGF receptor 2 (VEGFR-2) and maintains a basal expression level for VEGFR-2 and its downstream signaling activation.

Canonical and Noncanonical Vascular Endothelial Growth Factor ...

... VEGF from the endothelium uncovers a broad need for autocrine VEGF in the vasculature. ... Autocrine VEGF signaling is required for vascular homeostasis. Cell.

Mechanisms underlying context-dependent VEGF signaling for ...

... VEGF functions in the context of VEGF signaling is required. ANTI ... Autocrine VEGF signaling is required for vascular homeostasis. Cell 2007;130 ...