Axonal sensitivity and block dynamics

While highly myelinated nerves are more sensitive to local anesthetics than unmyelinated ones in vitro, factors influencing drug diffusion, ...

Axonal sensitivity and block dynamics - Yubetsu Shibata

While highly myelinated nerves are more sensitive to local anesthetics than unmyelinated ones in vitro, factors influencing drug diffusion, ...

High Frequency Stimulation Can Block Axonal Conduction - PMC

Although low frequency stimulation (LFS; orthodromic and antidromic) is commonly used to characterize hippocampal pathways and network dynamics (Leung 1979a; ...

Optimal Axonal and Dendritic Branching Strategies During the ...

In developing brain, axons and dendrites are capable of connecting to each other with high precision. Imaging of axonal and dendritic dynamics in vivo shows ...

Functional imaging of conduction dynamics in cortical and spinal ...

Reconstruction of axonal morphologies based on extracellular action potentials enables label-free electrical visualization of axonal ...

Modeling axonal regeneration by changing cytoskeletal dynamics in ...

More importantly, rapid and sensitive morphological changes of growth cones and fine protrusions in the distal axon were able to distinguish the ...

Article Prior Exposure to Neurotrophins Blocks Inhibition of Axonal ...

Here, inhibition by MAG, and myelin in general, is blocked if neurons are exposed to neurotrophins before encountering the inhibitor; priming cerebellar neurons ...

Unraveling axonal mechanisms of traumatic brain injury

However, heatmaps of individual axons show that the number of swellings per axon is dynamic in time (Fig. 2D, left). Indeed, some AS are present ...

Axon degeneration: Molecular mechanisms of a self-destruction ...

A proposed model of axon degeneration is that nerve insults lead to impaired delivery or expression of a local axonal survival factor.

Axonal blockage with microscopic magnetic stimulation - Nature

Clinically, HFS on the pudendal nerve was implemented for the treatment of the detrusor-sphincter dyssynergia, since it can block sphincter ...

Cortical acetylcholine dynamics are predicted by cholinergic axon ...

We observed a high correlation between axon and GRAB-ACh activity around periods of locomotion and pupil dilation. GRAB-ACh fluorescence could be accurately ...

Glycinergic axonal inhibition subserves acute spatial sensitivity to ...

A key component of the neuron doctrine is the unidirectional propagation of action potentials, formulated as the 'law of dynamic polarization' ...

Simulated auditory nerve axon demyelination alters sensitivity and ...

block. These increasing thresholds coincide with decreases in dynamic range (data not shown). Mean latencies of responses to cathodic monophasic stimuli, at ...

Axonal tree morphology and signal propagation dynamics improve ...

We demonstrate that utilizing the geometrical parameters of axonal tree structures significantly improves neuronal classification compared to the dendritic ...

Axonal Degeneration Is Regulated by the Apoptotic Machinery or a ...

However, the molecular mechanisms that govern developmental neurite pruning versus injury-induced neurite degeneration are still mostly unclear.

Evidence for axonal membrane hyperpolarization in multifocal motor ...

Evidence is presented to indicate that the axonal membrane just distal to the site of conduction block is abnormal in patients with MMN. Measurements of ...

Synaptic Dynamics Convey Differential Sensitivity to Input Pattern ...

Neither muscle showed consistent sensitivity to changes in the overall spike interval structure, but cpv2b was surprisingly sensitive to changes ...

Dynamics and sensitivity analysis of high-frequency conduction block

The local delivery of extracellular high-frequency stimulation (HFS) has been shown to be a fast acting and quickly reversible method of ...

Axonal degeneration in chemotherapy-induced peripheral ...

... dynamics may negatively affect both anterograde and retrograde axonal transport. ... Gene therapy targeting SARM1 blocks pathological axon degeneration in mice.

Enhanced Sensitivity of Striatal Neurons to Axonal Transport Defects ...

However, previous work did not resolve whether mutant huntingtin affects global axonal transport or only a subset of cargoes, nor did it resolve ...