Beyond the Liver

Gene delivery beyond the liver | Nature Nanotechnology

Gene delivery beyond the liver ... Lipid nanoparticles (LPNs) are used to carry therapeutic nucleic acids, such as mRNA (as in the case of the ...

Beyond the Liver: Liver-Eye Communication in Clinical and ...

Liver dysfunction caused by liver disease can cause liver cells to fail to normally take in unbound bilirubin in the blood, causing bilirubin metabolism ...

Strategies for non-viral vectors targeting organs beyond the liver

The enrichment of particular proteins on the NP surface apparently drives the transfection of specific targets. The discovery of new, powerful ...

Beyond the Biopsy - Global Liver Institute

Beyond the Biopsy program is a multifaceted awareness campaign dedicated to accelerating the acceptance and adoption of non-invasive diagnostics as an ...

Alkaline phosphatase: beyond the liver - PubMed

The alkaline phosphatases comprise a heterogeneous group of enzymes that are widely distributed in mammalian cells. They often are associated with cell ...

Progress and challenges of targeted delivery of siRNA therapeutics

Review. Going beyond the liver: Progress and challenges of targeted delivery of siRNA therapeutics.

Lipid Nanoparticles for Nucleic Acid Delivery Beyond the Liver

Overall, LNP-mediated nucleic acid delivery to the hepatocytes offers great therapeutic value, for treating liver diseases. Nevertheless, the nonintentional ...

Beyond the liver: a novel lipid library opening new horizons for LNP ...

Sponsor · A novel imidazolium-based lipid library: LipidBrick® · The benefits of innovative lipids on the properties of LNPs, whether as a total ...

Moving RNA Therapeutics Beyond the Liver - BioSpace

The Central Nervous System. RNAi therapies like Alnylam's Amvuttra and Onpattro (patisiran)—which both target the liver—work by silencing ...

Beyond a liver-gut focus: the evolution of gastroenterology and ...

Policy, educational and socially adjusted interventions to prevent obesity and obesity-related sequelae ... One promising enterprise is 'social prescribing', ...

Beyond the liver: The role of neurotensin in nonalcoholic fatty liver ...

Initially identified as a neuropeptide regulating primary homeostatic processes and energy balance, NT was later detected in intestinal ...

Beyond the Liver Neurologic Manifestations of Alcohol Use

Distinguishing alcohol-related neurologic complications from hepatic encephalopathy remains clinically challenging, and thorough history-taking ...

Recent trends in the delivery of RNA drugs: Beyond the liver, more ...

Abstract. RNAs are known for versatile functions and therapeutic utility. They have gained significant interest since the approval of several RNA drugs, ...

The Decade of RNA Delivery – Beyond the Liver - BioSpace

Using its AI/ML-based engine, Mana.bio designed a lipid nanoparticle (LNP)-based delivery system that is able to selectively target the lung, ...

Going Beyond The Liver In NAFLD/NASH - PanNASH Initiative

Hepatocellular carcinoma surveillance in NAFLD patients. Nonalcoholic fatty liver disease (NAFLD) is characterised by the presence of hepatic ...

Patient education: Metabolic dysfunction-associated steatotic liver ...

Patient education: Metabolic dysfunction-associated steatotic liver disease (Beyond the Basics). Formulary drug information for this topic.

5 Reasons You May Be at Risk for Liver Disease

By the time you show symptoms, your liver may be damaged beyond repair. The good news: people who stop drinking at the fatty liver stage may find their ...

A Radiologist's Guide to the Liver Blood Tests - RSNA Journals

Beyond the Liver Function Tests: A Radiologist's Guide to the Liver Blood Tests. Brandon M. Metra ,; Flavius F. Guglielmo,; Dina L. Halegoua ...

When Liver Disease Goes Beyond The Liver… - Amsety

Liver Disease Goes Beyond The Liver: Here Is How It Can Manifest. Multiple organs depend on a healthy liver. When the liver fails to carry out its functions ...

Alkaline phosphatase: beyond the liver - Fernandez, - 2007

Despite this, alkaline phosphatase activity is a very useful serum biochemical indicator of liver disease, particularly cholestatic disease.