Biobank scale pharmacogenomics informs the genetic ...

Biobank Scale Pharmacogenomics Informs the Genetic ... - PubMed

Studying drug-metabolizing enzymes, encoded by pharmacogenes, may inform biological mechanisms underlying the diseases for which a medication is prescribed.

Biobank Scale Pharmacogenomics Informs the Genetic ...

We used biobank-scale data to uncover and replicate an association between NAT2 locus variation and better response to statin therapy.

Biobank scale pharmacogenomics informs the genetic ... - medRxiv

We used biobank-scale data to uncover and replicate a novel association between NAT2 locus variation (and suggestive evidence with several other genes) and ...

Biobank Scale Pharmacogenomics Informs the Genetic ...

Biobank Scale Pharmacogenomics Informs the Genetic Underpinnings of Simvastatin Use. Frank R. Wendt, Dora Koller, Gita A. Pathak, Daniel Jacoby, Edward J ...

Biobank scale pharmacogenomics informs the genetic ...

Citations & impact. Biobank scale pharmacogenomics informs the genetic underpinnings of simvastatin use. Wendt FR ,. Koller D ,. Pathak GA ,. Jacoby D ,. Miller ...

Biobank Scale Pharmacogenomics Informs the Genetic ...

Request PDF | Biobank Scale Pharmacogenomics Informs the Genetic Underpinnings of Simvastatin Use | Studying drug‐metabolizing enzymes, ...

Biobank scale pharmacogenomics informs the genetic ... - CoLab

... Biobank scale pharmacogenomics informs the genetic underpinnings of simvastatin use. Wendt F.R., Koller D., Pathak G.A., Jacoby D., Miller E.J., Polimanti R ...

Pharmacogenetics at Scale: An Analysis of the UK Biobank - PubMed

Pharmacogenetics (PGx) studies the influence of genetic variation on drug response. Clinically actionable associations inform guidelines created by the ...

Biobank Scale Pharmacogenomics Informs the Genetic ... - CoLab

Studying drug-metabolizing enzymes, encoded by pharmacogenes, may inform biological mechanisms underlying the diseases for which a medication is prescribed.

Pharmacogenetics at scale: An analysis of the UK Biobank - bioRxiv

Abstract. Pharmacogenetics (PGx) studies the influence of genetic variation on drug response. Clinically actionable associations inform ...

From pharmacogenetics to pharmaco-omics: Milestones and future ...

Pharmacogenetics at scale: an analysis of the UK Biobank. Clin ... Biobank scale pharmacogenomics informs the genetic underpinnings of simvastatin use.

[PDF] The genetic architecture of medication-use | Semantic Scholar

UK Biobank and performed a GWAS to identify which common genetic ... Biobank Scale Pharmacogenomics Informs the Genetic Underpinnings of Simvastatin Use.

Evaluating the frequency and the impact of pharmacogenetic alleles ...

... genetic information may inform dosing in a large proportion of patients. ... Pharmacogenetics at scale: an analysis of the UK Biobank. Clin ...

Pharmacogenomics Beyond Single Common Genetic Variants

pharmacogenomic investigations. In particular ... Biobank scale pharmacoge- nomics informs the genetic underpinnings of simvastatin use.

Pharmacogenetics at scale: An analysis of the UK Biobank - bioRxiv

Pharmacogenetics (PGx) studies the influence of genetic variation on drug response. Clinically actionable associations inform guidelines ...

medRxiv в X: „Biobank scale pharmacogenomics informs the ...

Biobank scale pharmacogenomics informs the genetic underpinnings of simvastatin use https://t.co/qppv5L6j0D #medRxiv.

Drug Response Pharmacogenetics for 200,000 UK Biobank ...

Doctor's may not directly be using pharmacogenetics to inform practice, but genetics ... Pharmacogenetics at scale: An analysis of the UK Biobank ...

Pharmacogenomics Beyond Single Common Genetic Variants

Biobank scale pharmacogenomics informs the genetic underpinnings of simvastatin use. Clin. Pharmacol. Ther. 110:3777–85. [Google Scholar]. 94 ...

Large-Scale Pharmacogenomics Analysis of Patients With Cancer ...

PURPOSEAs part of the 100000 Genomes Project, we set out to assess the potential viability and clinical impact of reporting genetic variants ...

Frequencies of pharmacogenomic alleles across biogeographic ...

... scale genetic UK Biobank. Using the Pharmacogenomics Clinical Annotation Tool (PharmCAT),, and the UK Biobank, we estimated the frequencies of PGx ...