Biocatalytic Strategy for the Highly Stereoselective Synthesis of ...

A biocatalytic strategy for the stereoselective synthesis of mono-fluorinated and gem-difluoro cyclopropanes is reported though the use of engineered myoglobin ...

Fluorinated cyclopropanes are highly desired pharmacophores in drug discovery owing to the rigid nature of the cyclopropane ring and the ...

Biocatalytic Strategy for the Highly Stereoselective Synthesis of CHF ...

A biocatalytic method was developed for the highly diastereo- and enantioselective synthesis of CHF 2 -substituted cyclopropanes via myoglobin-catalyzed ...

Biocatalytic Strategy for the Highly Stereoselective Synthesis ... - CDN

Abstract: Fluorinated cyclopropanes are highly desired pharmacophores in drug discovery owing to the rigid nature of the cyclopropane ring ...

Biocatalytic strategy for the highly stereoselective synthesis of CHF2 ...

Using engineered myoglobin catalysts, a broad range of α-difluoromethyl alkenes are cyclopropanated in the presence of ethyl diazoacetate to give CHF2- ...

Biocatalytic Strategy for the Highly Stereoselective Synthesis of CHF2

Enantioselective Synthesis Hot Paper. Biocatalytic Strategy for the Highly Stereoselective Synthesis of CHF2-. Containing Trisubstituted Cyclopropanes. Daniela ...

Biocatalytic Strategy for the Highly Stereoselective Synthesis of ...

A biocatalytic strategy for the stereoselective synthesis of mono-fluorinated and gem-difluoro cyclopropanes is reported though the use of engineered ...

Biocatalytic Strategy for the Highly Stereoselective Synthesis of ...

Herein a biocatalytic strategy for the stereoselective synthesis of mono‐fluorinated and gem‐difluoro cyclopropanes is reported though the use ...

Biocatalytic Strategy for the Highly Stereoselective Synthesis of CHF 2

Biocatalytic Strategy for the Highly Stereoselective Synthesis of CHF2 -Containing Trisubstituted Cyclopropanes. Carminati DM 1 ,. Decaens J 2 ,. Couve ...

Biocatalytic Strategy for the Highly Stereoselective Synthesis of CHF 2

Using engineered myoglobin catalysts, a broad range of α‐difluoromethyl alkenes are cyclopropanated in the presence of ethyl diazoacetate to give CHF 2 ‐ ...

A Highly Stereoselective and Efficient Biocatalytic Synthesis of ...

Chiral aryl β-hydroxy α-amino acids and their derivatives are essential pharmaceutical intermediates, widely used as chiral building blocks ...

Rudi Fasan on LinkedIn: Biocatalytic Strategy for the Highly ...

Happy to share our latest work on the stereoselective synthesis of difluorocyclopropanes using engineered carbene transferases just appeared ...

Biocatalytic Strategy for the Highly Stereoselective Synthesis of ...

Request PDF | Biocatalytic Strategy for the Highly Stereoselective Synthesis of CHF2‐Containing Trisubstituted Cyclopropanes | The ...

Biocatalytic Strategy for the Highly Stereoselective Synthesis of CHF ...

Biocatalytic Strategy for the Highly Stereoselective Synthesis of CHF₂‐Containing Trisubstituted Cyclopropanes.

Highly Stereoselective Biocatalytic One-Pot Synthesis of Chiral ...

Highly Stereoselective Biocatalytic One-Pot Synthesis of Chiral Saturated Oxygen Heterocycles by Integration of a Biosynthetic Heterocyclase ...

Biocatalytic Strategy for the Highly Stereoselective Synthesis of CHF ...

Biocatalytic Strategy for the Highly Stereoselective Synthesis of CHF2 -Containing Trisubstituted Cyclopropanes. Carminati, Daniela M; Decaens, Jonathan; Couve- ...

Biocatalytic Strategy for the Highly Stereoselective Synthesis of CHF2

Biocatalytic Strategy for the Highly Stereoselective Synthesis of CHF2 -Containing Trisubstituted Cyclopropanes. Carminati, Decaens, Couve-Bonnaire, ...

Highly stereoselective and enantiodivergent synthesis of ...

In combination with a 'substrate walking' protein engineering strategy, two sets of efficient and enantiodivergent myoglobin-based biocatalysts ...

Veronica Tona on LinkedIn: Biocatalytic Strategy for the Highly ...

Check out my latest publication! In this work, we explore the use of photobiocatalysis for an enantioselective hydroamination reaction. This ...

Biocatalytic approaches towards the stereoselective synthesis of ...

Recent advances in biocatalysis, fueled either by protein engineering or by screening, have greatly improved the number of synthetic opportunities from small ...