CRISPR/Cas9 screen uncovers functional translation of cryptic ...

Emerging evidence suggests that cryptic translation within long noncoding RNAs (lncRNAs) may produce novel proteins with important ...

CRISPR/Cas9 screen uncovers functional translation of cryptic ... - JCI

CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer.

CRISPR/Cas9 screen uncovers functional - ProQuest

CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer ... You might have access to the full article...

(PDF) CRISPR/Cas9 screen uncovers functional translation of ...

CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer · Abstract and Figures.

CRISPR/Cas9 screen uncovers functional translation of cryptic ... - JCI

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CRISPR/Cas9 screen uncovers functional translation of cryptic ...

CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer. Citation metadata. Authors: Caishang Zheng ...

CRISPR–Cas9-based functional interrogation of unconventional ...

Emerging evidence suggests that cryptic translation beyond the annotated translatome produces proteins with developmental or physiological functions.

CRISPR/Cas9 screen uncovers functional translation of cryptic ...

Zheng C, Wei Y, Zhang P, Xu L, et al. CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer. J Clin ...

(PDF) CRISPR–Cas9-based functional interrogation of ...

Emerging evidence suggests that cryptic translation beyond the annotated translatome produces proteins with developmental or physiological ...

CRISPR screening uncovers nucleolar RPL22 as a heterochromatin ...

CRISPR/Cas9-mediated gene editing was performed as previously described (57,58). In brief, sgRNA targeting the first exon of the RPL22 gene was ...

Noncanonical open reading frames encode functional proteins ...

CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer · Medicine, Biology. Journal of Clinical ...

CRISPR-Cas9-based functional interrogation of unconventional ...

CRISPR-Cas9-based functional interrogation of unconventional translatome reveals human cancer dependency on cryptic non-canonical open reading frames.

Cryptic lncRNA-encoded ORFs: A hidden source of regulatory proteins

See the article "CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer" in volume 133 ...

Genome-scale exon perturbation screens uncover ... - Cell Press

CRISPR-Cas technology has transformed functional genomics, yet understanding of how individual exons differentially shape cellular ...

CRISPR screening uncovers nucleolar RPL22 as a heterochromatin ...

Dysfunction of the ribosome manifests during cellular senescence and contributes to tissue aging, functional decline, and development of aging-.

Genome-scale CRISPR-Cas9 screening in stem cells

The CRISPR-Cas9 technology now goes beyond creating single gene editing to enable the inhibition or activation of endogenous gene loci by fusing ...

A unified model for the surveillance of translation in diverse ... - bioRxiv

While the resulting polypeptides are often non-functional, translation in noncoding regions is nonetheless necessary for the birth of new coding ...

xiangdong lyu - GrantForward

CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer. C Zheng, Y Wei, P Zhang, L Xu, Z Zhang, K ...

Suppressive cancer nonstop extension mutations increase C ...

Nonstop extension mutations, a.k.a. stop-lost or stop-loss mutations, convert a stop codon into a sense codon resulting in translation into ...

Creation of de novo cryptic splicing for ALS/FTD precision medicine

10.1101/2023.10.20.563362: Genome-wide CRISPR/Cas9 screen identifies MAT2A as a critical host factor for BK Polyomavirus · 10.1101/2023.10 ...