CRISPR screening uncovers nucleolar RPL22 as a heterochromatin ...

Through this approach, we identified ribosomal protein L22 (RPL22) as the foremost RAG whose deficiency mitigates the effects of cellular ...

Our findings unveil a novel role for nucleolar RPL22 as a destabilizer of heterochromatin and a driver of cellular senescence.

CRISPR screening uncovers nucleolar RPL22 as a heterochromatin ...

Abstract. Dysfunction of the ribosome manifests during cellular senescence and contributes to tissue aging, functional decline, and development of aging-re.

CRISPR screening uncovers nucleolar RPL22 as a heterochromatin ...

Request PDF | On Sep 11, 2024, Hong-Yu Li and others published CRISPR screening uncovers nucleolar RPL22 as a heterochromatin destabilizer ...

CRISPR screening uncovers nucleolar RPL22 as a heterochromatin ...

Abstract Dysfunction of the ribosome manifests during cellular senescence and contributes to tissue aging, functional decline, and development of ...

Ribosomal Protein RPL22 Drives Human Stem Cell Aging: Study

... CRISPR/Cas9 gene screening technology. ... Reference. CRISPR screening uncovers nucleolar RPL22 as a heterochromatin destabilizer and senescence ...

CRISPR screening uncovers nucleolar RPL22 as a heterochromatin ...

CRISPR screening uncovers nucleolar RPL22 as a heterochromatin destabilizer and senescence driver. CRISPR筛选揭示核仁RPL22作为异染色质去稳定 ...

CRISP_SCIENCE on X: "#CRISPR screening uncovers nucleolar ...

CRISPR screening uncovers nucleolar RPL22 as a heterochromatin destabilizer and senescence driver" Li HY, Wang M, Jiang X, Jing Y [.

CRISPR-based screening pinpoints H2AZ1 as a driver of ...

CRISPR screening uncovers nucleolar RPL22 as a heterochromatin destabilizer and senescence driver. Article. Sep 2024; NUCLEIC ACIDS RES. Hong-Yu Li · Min Wang ...

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ヘテロクロマチン不安定化因子および老化促進因子として核小体 ...

[出典] "CRISPR screening uncovers nucleolar RPL22 as a heterochromatin destabilizer and senescence driver" Li HY, Wang M, Jiang X, Jing Y [.

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CRISPR screening uncovers nucleolar RPL22 as a heterochromatin destabilizer and senescence driver. Li, Hong-Yu; Wang, Min; Jiang, Xiaoyu; Jing ...

Destabilizing heterochromatin by APOE mediates senescence.

... nuclear lamina proteins and a heterochromatin ... CRISPR screening uncovers nucleolar RPL22 as a heterochromatin destabilizer and senescence driver.

OUCI

CRISPR screening uncovers nucleolar RPL22 as a heterochromatin destabilizer and senescence driver. Hong-Yu Li, Min Wang, Xiaoyu Jiang, Yaobin Jing, Zeming Wu ...

A multiparametric anti-aging CRISPR screen uncovers a role for ...

... heterochromatin at the nuclear periphery (Fig. 1A). On the contrary to primary NGPS cells being unable to proliferate in culture (personal ...

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CRISPR screening uncovers nucleolar RPL22 as a heterochromatin destabilizer and senescence driver. Authors : Li HY; Key Laboratory of Biomacromolecules (CAS) ...

Evidence of the Physical Interaction between Rpl22 and the ... - MDPI

In this work, we tested the hypothesis that the remnants of the Doc5 transposable element, which retains a heterochromatin insertion pattern in the melanogaster ...

heterochromatin protein 1gamma (HP1gamma) - Allie (アリー): 略語 ...

CRISPR screening uncovers nucleolar RPL22 as a heterochromatin destabilizer and senescence driver. KAP1, LOF, RAGs, RPL22, hMPCs, rRNAs. 2. 2023. Signal ...

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CRISPR screening uncovers nucleolar RPL22 as a heterochromatin destabilizer and senescence driver. Pregnant women experiencing homelessness struggle to access ...

RPL22 is a tumor suppressor in MSI-high cancers and a key splicing ...

To test the loss of RPL22, we performed CRISPR/Cas9 knockout of RPL22 in ... Uncovered by Large-Scale, Deep RNAi Screening. Cell 170, 577–592.e10 (2017) ...