Can a Monoclonal Antibody Prevent Influenza?

New antibody-based prevention and treatment options for influenza

In the past decade, a number of human monoclonal antibodies have been described that can bind to and neutralize a broad range of influenza A and B viruses. Most ...

Can a Monoclonal Antibody Prevent Influenza? - NEJM Journal Watch

Can a Monoclonal Antibody Prevent Influenza? ... The monoclonal antibody VIR-2482 — which targets a conserved region in influenza's hemagglutinin ...

Antibodies may aid effort to fight influenza B: study - VUMC News

The findings reported in the journal Immunity support the development of a monoclonal antibody for prevention and treatment of influenza B ...

Monoclonal Antibody Therapy Protects Pharmacologically ...

The expression of proinflammatory cytokines/chemokines can be instrumental in controlling influenza virus infection (38); in the immunosuppressed host, even ...

Anti-influenza monoclonal antibodies to hemagglutinin (HA) that are ...

Monoclonal antibodies (mAbs) that target specific strains and subtypes of influenza HA can ... prevention, and to improve quality control ...

A pan-influenza monoclonal antibody neutralizes H5 strains ... - Nature

Prophylactic monoclonal antibodies could prevent community spread in the period before and during vaccination campaigns, but pre-exposure ...

Protective human monoclonal antibodies target conserved sites of ...

Current influenza vaccines mainly induce antibodies against the surface glycoprotein hemagglutinin (HA) that can block viral attachment to its ...

A broadly protective human monoclonal antibody targeting the ...

There is, therefore, an urgent need to develop vaccines or therapeutics that protect against a wide range of influenza subtypes or lineages.

Airway Delivery of Anti-influenza Monoclonal Antibodies Results in ...

Because influenza vaccination can be poorly effective some years, and the immune systems of the most susceptible populations are often compromised, passive ...

Antibodies may aid effort to fight influenza B - ScienceDaily

Small-molecule drugs that block neuraminidase, a major surface glycoprotein of the influenza virus, can help treat ...

Low Dose Pig Anti-Influenza Virus Monoclonal Antibodies Reduce ...

Low Dose Pig Anti-Influenza Virus Monoclonal Antibodies Reduce Lung Pathology but Do Not Prevent Virus Shedding ... We have established the pig, a large natural ...

Newly identified antibodies block many influenza strains in ...

The two newly identified antibodies inhibit viral proliferation in multiple strains of influenza, including lethal H3N2 infection in mice.

Antibody-Based Strategies to Prevent and Treat Influenza - Frontiers

More recently, monoclonal antibodies (mAbs) for viral infections have been developed, including licensure of Synagis for prevention of RSV infection. mAbs for ...

Broadly Protective Monoclonal Antibodies against H3 Influenza ...

Three monoclonal antibodies have been identified that are broadly-neutralizing against H3 influenza viruses spanning 40 years.

a monoclonal antibody for the prevention of severe influenza A illness

Vaccine-elicited antibodies primarily target the immunodominant HA head and block virus attachment to cells; however, due to frequent mutations in the head ...

Neutralizing Anti-Hemagglutinin Monoclonal Antibodies Induced by ...

Here, we will review a novel passive immunization method using antibody-gene transfer to protect against influenza virus infection and discuss ...

Vaccines and monoclonal antibodies in immunization - Sanofi

Monoclonal antibodies could also help protect infants when infectious diseases spread during their first year of life.11,12,13. Scientists are ...

Prophylactic and Therapeutic Efficacy of Human Monoclonal ... - PLOS

One possibility is passive immunotherapy—treating people with antibodies (proteins that recognize antigens) that can stop H5N1 from infecting cells (so-called ...

Monoclonal Antibodies Fact Sheet – NFID

Monoclonal antibodies (mAbs) are used to treat many diseases including COVID-19 and respiratory syncytial virus (RSV). This NFID fact sheet provides ...

How human monoclonal antibodies neutralize the flu virus - YouTube

This animation illustrates how directing monoclonal antibodies to the influenza virus prevents a conformational change in the protein that ...