Catalytic Amyloids as Novel Synthetic Hydrolases

Catalytic Amyloids as Novel Synthetic Hydrolases - PubMed

Amyloids are supramolecular assemblies composed of polypeptides stabilized by an intermolecular beta-sheet core.

Catalytic Amyloids as Novel Synthetic Hydrolases - MDPI

Here, we review the latest advances in this area, with particular emphasis on the design and development of catalytic amyloids that exhibit hydrolytic ...

[PDF] Catalytic Amyloids as Novel Synthetic Hydrolases | Semantic ...

The highly stable nature of the amyloid fold can provide an attractive alternative for the design of future synthetic hydrolases with diverse applications ...

Catalytic Amyloids as Novel Synthetic Hydrolases - ResearchGate

Conclusions: The phosphoanhydride bonds appear as the main specificity target of the Mn2+-amyloid complex. A single aspartate per peptide is ...

Catalytic Amyloids as Novel Synthetic Hydrolases - OUCI

The highly stable nature of the amyloid fold can provide an attractive alternative for the design of future synthetic hydrolases with diverse applications in ...

Catalytic Amyloids as Novel Synthetic Hydrolases | CoLab

Amyloids are supramolecular assemblies composed of polypeptides stabilized by an intermolecular beta-sheet core. These misfolded conformations have been ...

Chemical catalysis by biological amyloids - PMC

The detected catalytic activity was much less than that of 'real' enzymes, but like that of designed (synthetic) catalytic amyloids. I here ...

Catalytic amyloids - ScienceDirect.com

Amyloid fibril assemblies of proteins and synthetic peptides exhibit in some instances catalytic activities. · Reactions catalyzed by peptide amyloids include ...

Design and Testing of Synthetic Catalytic Amyloids Based on the ...

Catalytic Amyloids as Novel Synthetic Hydrolases. Duran-Meza E, Diaz-Espinoza R · Int J Mol Sci, 22(17):9166, 25 Aug 2021. Cited by: 6 articles | PMID ...

Amyloid Fibers of α-Synuclein Catalyze Chemical Reactions

It was proposed that the amyloid fibers, due to their polymeric nature, display distinct catalytic sites at the fibril's surface. (19) To assess ...

Amyloid Fibers of α‑Synuclein Catalyze Chemical Reactions

Amyloid fibers, but not monomers, of α-synuclein catalyzed hydrolysis of the model ester para-nitrophenyl acetate and dephosphorylation of the ...

Amyloid Fibrils Formed by Short Prion-Inspired Peptides Are ...

Hydrolases, especially esterases, are the most common artificial amyloid-like nanozymes with some reported to act as carbonic anhydrases (CA).

Catalytically Active Amyloids as Future Bionanomaterials - MDPI

The highly ordered amyloid structure provides repetitive active sites along the surface, which can promote bidimensional catalysis [42]. The ...

Synergistic Interactions Are Prevalent in Catalytic Amyloids ...

... amyloids with diverse catalytic efficiencies that directly depend on the non-catalytic X residue. ... Catalytic Amyloids as Novel Synthetic Hydrolases.

Chemical catalysis by biological amyloids - OUCI

... artificial peptide amyloids are developed into novel nanomaterials. ... Catalytic amyloids as novel synthetic hydrolases, Int. J. Mol. Sci., № 22, с ...

Asymmetric Michael addition catalysed by copper–amyloid complexes

Amyloid fibrils functioning as competent catalytic scaffolds are called catalytic amyloids. ... Unlike other artificial supramolecular compounds, ...

Amyloid and the origin of life: self-replicating catalytic amyloids as ...

The self-assembly of short peptides into β-sheet amyloid conformers leads to extraordinary structural stability and novel multifunctionality ...

Cross-β amyloid nanotubes for hydrolase-peroxidase cascade ...

Catalytic Amyloids as Novel Synthetic Hydrolases · Eva Duran-MezaRodrigo Diaz-Espinoza. Chemistry, Medicine. International journal of molecular sciences. 2021.

Extremophilic behavior of catalytic amyloids sustained by backbone ...

2021: Catalytic Amyloids as Novel Synthetic Hydrolases International Journal of Molecular Sciences 22(17) · Marshall, L.R.; Korendovych, I.V. 2021: Catalytic ...

Switchable Hydrolase Based on Reversible Formation of ...

Catalytic Amyloids as Novel Synthetic Hydrolases. ; Int J Mol Sci, 22(17):9166, 25 Aug 2021 ; Cited by: 4 articles | PMID: 34502074 ; Review Free to read & use ...