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Cell Signalling and Immunology


Overview of the Immune System | Cell Signaling Technology

Immunology-based research focuses on the components of the human immune system and the possibility of their use to combat various diseases.

Introduction to immune cell signalling - PubMed

The dynamic interaction of cells of the immune system with other cells, antigens and secreted factors determines the nature of an immune response.

Signaling Through Immune System Receptors - Immunobiology - NCBI

Cells communicate with their environment through a variety of cell-surface receptors that recognize and bind molecules present in the extracellular ...

Immune Cell Signaling Pathways - GeneGlobe - QIAGEN

Immune Cell Signaling. Immune cell signaling pathways are vital for orchestrating the body's defense against infections and injuries. By controlling how immune ...

Immune System Signaling Pathways | Clincical Guidance - Healio

NK cell activation, like T cells, is controlled by a dynamic balance between stimulatory and inhibitory signaling pathways. Upon activation, the surface ...

Cell Signalling and Immunology | University of Dundee, UK

Our work is relevant to the pathologies associated with cancer, diabetes, infectious disease, autoimmunity and allergy.

T cell receptor (TCR) signaling in health and disease - Nature

T cell signaling is thus important for efficient T cell development, activation, and immune tolerance. TCR signaling dysregulation can thus lead ...

Mechanistic Models of Cellular Signaling, Cytokine Crosstalk, and ...

The cells of the immune system respond to a great variety of different signals that frequently reach them simultaneously. Computational models of signaling ...

Cell Signaling Pathways | Thermo Fisher Scientific - US

Cytokines, chemokines (a type of cytokine), and growth factors are proteins that act as immune signaling molecules. They are many roles for cytokines in ...

Immunology and Immuno-Oncology - Cell Signaling Technology

Diverse selection of antibodies to generate critical information for the development of novel immunotherapies and insights into the role of immune cells and ...

Signal Transduction in Immune Cells: Receptor-Ligand Interactions

Now that we know some things about immune cell structure and function, we need to start understanding how these cells interact on the ...

Biophysics of immune cell signaling

Cells can be potent as individuals and can also mobilize collective responses to an insult or injury. Fluorescence imaging has played a central role in ...

Regulatory mechanisms in T cell receptor signalling - Nature

T cells are a major component of the adaptive immune response, playing a central role in pathogen elimination and tumour surveillance. In the ...

Cellular signaling in the aging immune system - ScienceDirect.com

Highlights. •. There is a general signal transduction alteration in immune cells with human aging. •. The most important changes occur at the proximal signaling ...

Editorial: T-Cell Signaling Networks in Health and Disease - Frontiers

Intracellular signaling networks control every aspect of T cell biology. Proper signaling promotes T cell development, cellular differentiation, adaptive immune ...

T-Cell Signaling - an overview | ScienceDirect Topics

T-cell signaling occurs upon formation of the immunological synapse, and binding of the TCR to the peptide-presenting MHC molecule expressed on the APC.

Cell Signalling and Immunology – Research Outputs — Discovery

(Lead / Corresponding author), Jun 2024, In: Plant and Cell Physiology. 65, 6, p. 999-1013 15 p., pcae041. Research output ...

Introduction to immune cell signalling | Parasitology | Cambridge Core

In this review we will first outline the general principles of intracellular signal transduction. We will then describe the signalling pathways triggered ...

Cell Surface Signaling Molecules in the Control of Immune Responses

Primary signal is received by the receptors on certain immune cell types; then these cells can induce several early downstream biochemical ...

Adaptor proteins: Flexible and dynamic modulators of immune cell ...

Secondly, as adaptor proteins do not possess enzymatic activity, enzymes involved in cellular signalling are excluded. For instance, a kinase ...