Cellular Pathophysiology of Leptospirosis
Cellular Pathophysiology of Leptospirosis: Role of Na/K-ATPase
We overview the role of Na/K-ATPase during leptospirosis infection as a potential therapeutic target or an indicator of disease severity.
Leptospirosis Pathophysiology: Into the Storm of Cytokines - Frontiers
Leptospirosis is a neglected tropical zoonosis caused by pathogenic spirochetes of the genus Leptospira. Infected reservoir animals ...
Leptospirosis: Practice Essentials, Background, Pathophysiology
The most consistent pathologic finding in leptospirosis is vasculitis of capillaries, manifested by endothelial edema, necrosis, and lymphocytic ...
When illness occurs, a broad array of organ systems may be involved, reflecting the systemic nature of the infection. As a result, the signs and symptoms of ...
Pathogenesis of leptospirosis: Cellular and molecular aspects
Leptospira possesses a high level of redundancy in virulence factors. Many putative adhesins have been identified but not confirmed genetically.
Leptospirosis: Pathogenesis, Clinical and Epidemiological Aspects
The molecular and cellular pathogenesis of leptospirosis remains poorly understood. Based on comparative bacterial genomics data, we recently identified the ...
(PDF) Cellular Pathophysiology of Leptospirosis: Role of Na/K-ATPase
Leptospirosis involves diverse molecular mechanisms and alteration in patient inflammatory and metabolic status. Nonetheless, Na/K-ATPase is ...
Pathology and pathogenesis of human leptospirosis: a commented ...
It was speculated at the time that the damage to cell membranes could be the result of hypothetical toxins produced by pathogenic leptospires, since it has been ...
Leptospiral Infection, Pathogenesis and Its Diagnosis—A Review
The chromosomal DNA of leptospires is distributed along the length of the cell, rather than the center [39]. Like most Gram-negative bacteria, Leptospira spp.
Leptospira: the dawn of the molecular genetics era for an emerging ...
These findings suggest that leptospires use host cell entry and rapid translocation as mechanisms to spread to target organs and evade immune killing. Infection ...
Cellular Pathophysiology of Leptospirosis: Role of Na/K-ATPase
Its cellular pathophysiology must involve a ubiquitous cellular mechanism in all eukaryotes. Na/K-ATPase is the molecular target of the leptospiral endotoxin ( ...
Leptospira - Pathology Outlines
Leptospira · Leptospirosis is a neglected zoonotic disease, caused by pathogenic species of Leptospira, a spirochete gram negative bacteria; the ...
Leptospirosis pathophysiology - wikidoc
Leptospires shed in the urine of animals to the environment from where humans are infected by incidental hosts.
Cleavage of cell junction proteins as a host invasion strategy in ...
While the probable mechanism of host invasion and pathogenesis is known in many pathogens, very little information is available on Leptospira ...
Leptospirosis: Aspects of Innate Immunity, Immunopathogenesis ...
interrogans are able to bind endothelial cells, monocytes/macrophages, kidney epithelial cells and fibroblast cell line cultures in vitro [23, ...
Signs and symptoms can range from none to mild (headaches, muscle pains, and fevers) to severe (bleeding in the lungs or meningitis). Weil's disease (/ˈvaɪlz ...
Epidemiology, microbiology, clinical manifestations, and diagnosis
Leptospira are spiral-shaped, highly motile aerobic spirochetes with 18 or more coils per cell. The organism stains poorly with common ...
(PDF) Leptospirosis Pathophysiology: Into the Storm of Cytokines
Leptospirosis is a neglected tropical zoonosis caused by pathogenic spirochetes of the genus Leptospira. Infected reservoir animals ...
Leptospirosis: pathogenesis, clinical and epidemiological aspects
Thus, tharapies targeting Leptospira adhesins may be an efficient way to prevent or limit infection by this spirochete. Frontiers in Cellular ...
Leptospirosis Pathophysiology and Treatment | Microbiology Video ...
Leptospirosis Pathophysiology and Treatment | Microbiology Video Lecture - Complete Lectures on sqadia.com ...