- Cellular prion protein mediates the toxicity of beta|amyloid oligomers🔍
- Cellular Prion Protein Mediates the Toxicity of β|Amyloid Oligomers🔍
- Cellular Prion Protein as a Receptor of Toxic Amyloid|β42 ...🔍
- Review Prion Protein as a Toxic Acceptor of Amyloid|β Oligomers🔍
- Prion Protein|mediated Toxicity of Amyloid|β Oligomers Requires ...🔍
- Cellular Prion Protein Mediates the Toxicity of Я|Amyloid Oligomers🔍
- Prion Protein as a Toxic Acceptor of Amyloid|b Oligomers🔍
- Alzheimer's Amyloid|β Oligomers Rescue Cellular Prion Protein ...🔍
Cellular Prion Protein Mediates the Toxicity of β|Amyloid Oligomers
Cellular prion protein mediates the toxicity of beta-amyloid oligomers
Herein, we review the recently published finding that cellular prion protein (PrP(c)) is a high-affinity receptor for Abeta oligomers, mediating their toxic ...
Cellular Prion Protein Mediates the Toxicity of β-Amyloid Oligomers
β-Amyloid oligomers have been found to be potent synaptotoxins, but the mechanism by which they exert their action has remained elusive. Herein, we review the ...
Cellular Prion Protein Mediates the Toxicity of β-Amyloid Oligomers
β-Amyloid oligomers have been found to be potent synaptotoxins, but the mechanism by which they exert their action has remained elusive. Herein, we review the ...
Cellular Prion Protein as a Receptor of Toxic Amyloid-β42 ... - Frontiers
PrPC mediates at a certain extent of the toxic effects of Aβ oligomers and thus plays an important role in AD pathogenesis (Salazar and ...
Review Prion Protein as a Toxic Acceptor of Amyloid-β Oligomers
The initial report that cellular prion protein (PrPC) mediates toxicity of amyloid-β species linked to Alzheimer's disease was initially treated with ...
Prion Protein-mediated Toxicity of Amyloid-β Oligomers Requires ...
The cellular prion protein (PrPC) was recently identified as a high affinity neuronal receptor for Aβ oligomers. We report that fibrillar Aβ oligomers ...
Cellular Prion Protein Mediates the Toxicity of Я-Amyloid Oligomers
Cellular Prion Protein Mediates the Toxicity of Я-Amyloid Oligomers. Implications for Alzheimer Disease. Haakon B. Nygaard, MD; Stephen M. Strittmatter, MD ...
Prion Protein as a Toxic Acceptor of Amyloid-b Oligomers
The initial report that cellular prion protein (PrPC) mediates toxicity of amyloid-b species linked to Alzheimer's disease was initially treated ...
Alzheimer's Amyloid-β Oligomers Rescue Cellular Prion Protein ...
... oligomers, (9, 10) whether PrPC mediates Aβ oligomer toxicity is still controversial. It has been shown that PrPC mediates the toxic effect of Aβ oligomers ...
Cellular Prion Protein Mediates the Toxicity of -Amyloid Oligomers ...
The recently published finding that cellular prion protein (PrP c) is a high-affinity receptor for A oligomers, mediating their toxic effects on synaptic ...
Full article: β-amyloid oligomers and prion protein - Taylor & Francis
We also tested the involvement of PrPC in mediating Aβ oligomer toxicity in vitro, by investigating their effect on survival of primary hippocampal neurons from ...
Prion protein stabilizes amyloid-β (Aβ) oligomers and enhances Aβ ...
Resenberger U.K., Winklhofer K.F., Tatzelt J. Cellular prion protein mediates toxic signaling of amyloid β. Neurodegener Dis, 10 (2012), pp. 298-300. 10.1159 ...
Cellular prion protein is essential for oligomeric amyloid-β-induced ...
However, other reports questioned these findings by noting that lack of PrPC did not prevent Aβ oligomer-mediated synaptic toxicity or cognitive impairment (3–5) ...
Cellular Prion Protein as a Receptor of Toxic Amyloid-β42 ...
Several studies have shown that interaction of Aβ oligomers with N-terminal residues of the PrPc protein region appears critical for neuronal toxicity, ...
Amyloid-β Receptors: The Good, the Bad, and the Prion Protein
... amyloid-β oligomers ... mediated toxicity of amyloid-β oligomers requires ... Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β ...
Cellular Prion Protein Mediates the Toxicity of beta-Amyloid ...
Request PDF | Cellular Prion Protein Mediates the Toxicity of beta-Amyloid Oligomers Implications for Alzheimer Disease | Alzheimer disease (AD) is the most ...
Full article: Cellular prion protein and Alzheimer disease
Soluble oligomeric amyloid-β (Aβ) has been suggested to impair synaptic and neuronal function, leading to neurodegeneration that is clinically observed as the ...
Interaction between prion protein and toxic amyloid β assemblies ...
... Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers. Nature 457, 1128–1132 (2009). Article ADS CAS ...
Prion Protein-mediated Toxicity of Amyloid-β Oligomers Requires ...
Balducci, Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein, Proc. Natl. Acad. Sci. U.S.A., № 107, с. 2295 https ...
The cellular prion protein mediates neurotoxic signalling of β‐sheet ...
An oligomer‐specific antibody and an NMDA receptor antagonist prevent toxic signalling of Aβ oligomers, PrPSc and β‐peptide. (A, B) SH‐SY5Y cells expressing GPI ...