Cellular Senescence
Cellular senescence in ageing: from mechanisms to therapeutic ...
Cellular senescence, first described in vitro in 1961, has become a focus for biotech companies that target it to ameliorate a variety of ...
Cellular senescence: the good, the bad and the unknown - Nature
Cellular senescence is a ubiquitous process with roles in tissue remodelling, including wound repair and embryogenesis.
Cellular senescence - Wikipedia
Cellular senescence is a phenomenon characterized by the cessation of cell division. ... In their experiments during the early 1960s, Leonard Hayflick and Paul ...
Does cellular senescence hold secrets for healthier aging?
researchers are exploring whether learning to harness a cellular state known as senescence — during which damaged cells resist removal by ...
Overview of Cellular Senescence and Aging
Cellular senescence is stable cell cycle arrest linked to aging and cancer and other disease states, including those associated with inflammation.
Mechanisms of Cellular Senescence: Cell Cycle Arrest ... - Frontiers
Cellular senescence is a stable cell cycle arrest that can be triggered in normal cells in response to various intrinsic and extrinsic stimuli, ...
Cellular Senescence - an overview | ScienceDirect Topics
Cellular senescence is the response of cells that results in stable cell cycle arrest and different phenotypic variations.
Cellular senescence: a key therapeutic target in aging and diseases
Cellular senescence is a hallmark of aging defined by stable exit from the cell cycle in response to cellular damage and stress.
Guidelines for minimal information on cellular senescence ...
Autofluorescence removal, multiplexing, and automated analysis methods for in-vivo fluorescence imaging
Definition of senescence - NCI Dictionary of Cancer Terms
The process of growing old. In biology, senescence is a process by which a cell ages and permanently stops dividing but does not die.
Cellular Senescence: Defining a Path Forward - ScienceDirect
Cellular senescence is a cell state triggered by stressful insults and certain physiological processes, characterized by a prolonged and ...
Cellular senescence in normal physiology - Science
Cellular senescence in normal physiology. Long associated with aging, senescent cells can promote health and have physiological roles.
Mechanisms and functions of cellular senescence - JCI
By imposing a growth arrest, senescence limits the replication of old or damaged cells. Besides exiting the cell cycle, senescent cells undergo ...
Cellular Senescence: Defining a Path Forward - Cell Press
Cellular senescence is a cell state triggered by stressful insults and certain physiological processes, characterized by a prolonged and ...
Cellular Senescence: What, Why, and How
Cellular senescence is an essentially irreversible growth arrest that occurs in response to various cellular stressors, such as telomere erosion, DNA damage, ...
For aging specifically in humans, see Ageing. For plants, see Plant senescence. For cells that stop dividing, see Cellular senescence. For bacteria, see ...
Cellular Senescence - Reactome Pathway Database
Cellular senescence can be triggered by the aberrant activation of oncogenes or loss-of-function of tumor suppressor genes, and this type of senescence is known ...
Cellular senescence: beneficial, harmful, and highly complex - Baker
Functionally, cellular senescence can prevent the division of cells exhibiting excessive DNA damage or other macromolecular damage. Once thought ...
Cellular senescence: Neither irreversible nor reversible
The view of senescence as an irreversible arrest is closely linked to its understanding as a binary condition—being in or not—thereby implying a ...
Overview of Cell Senescence - YouTube
Researchers have found that senescent cells accumulate in our body as we age. Deciphering the purpose, causes, and consequences of cellular ...