Cellular fate of a plant virus immunotherapy candidate

Cellular fate of a plant virus immunotherapy candidate - Nature

Cowpea mosaic virus (CPMV) is a plant virus that is currently being developed for intratumoral immunotherapy. CPMV relieves the immune ...

Cellular fate of a plant virus immunotherapy candidate - PubMed

We show that murine macrophage immune cells recognize CPMV; however, there is no indication of de novo viral protein synthesis or RNA ...

Cellular fate of a plant virus immunotherapy candidate. - eScholarship

We show that murine macrophage immune cells recognize CPMV; however, there is no indication of de novo viral protein synthesis or RNA replication. Furthermore, ...

Cellular fate of a plant virus immunotherapy candidate - ResearchGate

We show that murine macrophage immune cells recognize CPMV; however, there is no indication of de novo viral protein synthesis or RNA ...

Cellular fate of a plant virus immunotherapy candidate - OUCI

AbstractCowpea mosaic virus (CPMV) is a plant virus that is currently being developed for intratumoral immunotherapy. CPMV relieves the immune system from ...

Pharmacology of a Plant Virus Immunotherapy Candidate for ...

Our lab has identified a plant virus nanoparticle, cowpea mosaic virus (CPMV) as a promising approach for cancer immunotherapy. When ...

Publications - Steinmetz Lab

... Cellular fate of a plant virusimmunotherapy candidate. Communications ... Pharmacology of a Plant Virus Immunotherapy Candidate for Peritoneal Metastatic Ovarian ...

Plant Virus Intratumoral Immunotherapy with CPMV and PVX Elicits ...

Scale bar = 50 μm. Quantification of confocal images show immune cell infiltration into tumors. (C) Both CPMV and PVX lead to an increase in ...

The Role of the Microenvironment and Immune System in ...

Related Items. Cellular fate of a plant virus immunotherapy candidate. Omole, Anthony;; Affonso de Oliveira... VH2+ Antigen-Experienced B Cells in the ...

Plant Virus Intratumoral Immunotherapy with CPMV and PVX Elicits ...

Plant Virus Intratumoral Immunotherapy with CPMV and PVX Elicits Durable Antitumor Immunity in a Mouse Model of Diffuse Large B-Cell Lymphoma.

Plant Viruses as Adjuvants for Next-Generation Vaccines and ...

According to current research, it is evident that plant viruses have great potential for application in the development of vaccines and in cancer immunotherapy.

Future of Cancer Immunotherapy using Plant virus-based ...

Plant viruses can be taken up by tumor cells and can be functionalized as drug delivery vehicles. This Special Report describes how the future of cancer ...

Researchers Shed Light on Why a Certain Plant Virus Is So ...

Each immunotherapy candidate was administered in three doses given 7 days apart. Mice given the cowpea mosaic virus nanoparticles had the ...

Advances in cell-based delivery of oncolytic viruses as therapy for ...

Carrier cells, which can even have innate tumor tropism, have shown their appropriateness as effective vehicles for systemic oncolytic virus ...

In vitro and in vivo studies of plant-produced Atezolizumab as a ...

Cellular fate of a plant virus immunotherapy candidate. Article Open ... Immune checkpoint inhibitors (ICIs), adoptive cell transfer therapy ...

Therapeutic bacteria and viruses to combat cancer: double-edged ...

Numerous OVs have been studied for their methods of action and impacts on immunogenic cell death, apoptosis, autophagy, and immune system ...

Reconceptualizing Cancer Immunotherapy Based on Plant ...

The use of nanoparticle technology based on plant viruses as a novel strategy to target and combat cancers is also included. The review concludes with a ...

Recombinant helical plant virus-based nanoparticles for vaccination ...

Thus, chimeric BVP1 virions expressing a partial sequence of VP1 protected target animals by generating humoral and cell-mediated immune ...

Plant Virus Nanoparticles for Anti-cancer Therapy - Frontiers

Furthermore, many plant viral VLPs possess inherent adjuvant properties dispensing with the requirement of additional adjuvants to stimulate immune activity.

Identification of Plant Virus Receptor Candidates in the Stylets of ...

Because noncirculative viruses are acquired when plant sap or cell contents are pumped through the stylets and released when saliva is spitted out, their ...