Cellular senescence impairs the reversibility of pulmonary arterial ...

Pulmonary arterial hypertension (PAH) in congenital cardiac shunts can be reversed by hemodynamic unloading (HU) through shunt closure.

Working model for the role of cellular senescence in vascular remodeling in PAH. Fig. S2. Matrix of vascular cell type–specific genes.

Cellular senescence impairs the reversibility of pulmonary arterial ...

The transition from reversible to irreversible pulmonary arterial hypertension involves vascular senescence and can be countered by senolysis.

Cellular senescence in the pathogenesis of pulmonary arterial ...

Cellular senescence impairs the reversibility of pulmonary arterial hypertension. Sci Transl Med. (2020) 12. doi: 10.1126/scitranslmed ...

Cellular senescence impairs the reversibility of pulmonary arterial ...

van der Feen, Diederik E ; Bossers, Guido P L ; Hagdorn, Quint A J et al. / Cellular senescence impairs the reversibility of pulmonary arterial ...

Eliminating Senescent Cells Can Promote Pulmonary Hypertension ...

Cellular senescence impairs the reversibility of pulmonary arterial hypertension. Sci Transl Med. 2020;12:eaaw4974. doi: 10.1126 ...

Cellular senescence impairs the reversibility of pulmonary arterial ...

PDF | Pulmonary arterial hypertension (PAH) in congenital cardiac shunts can be reversed by hemodynamic unloading (HU) through shunt closure ...

Cellular senescence impairs the reversibility of pulmonary arterial ...

This study used MCT+shunt-induced PAH in rats to identify a dichotomous reversibility response to HU, and compared vascular profiles of ...

Senescence in pulmonary arterial hypertension: is there a link?

Cellular senescence impairs the reversibility of pulmonary arterial hypertension. Sci Transl Med 2020; 12:eaaw4974. Cited Here |; Google Scholar. 26 ...

Endothelial cell senescence exacerbates pulmonary hypertension ...

Kok, et al. Cellular senescence impairs the reversibility of pulmonary arterial hypertension. Sci. Transl. Med., 12 (2020), p. eaaw4974. View ...

Senescence Alterations in Pulmonary Hypertension - MDPI

Cellular senescence impairs the reversibility of pulmonary arterial hypertension. Sci. Trans. Med. 2020, 12, 554. [Google Scholar] [CrossRef]; Sugimoto, K ...

Converging Paths of Pulmonary Arterial Hypertension and Cellular ...

Senescent EC also lose their ability to form new vessels and seem to impair normal angiogenesis in their vicinity (27). The hypothesis that DNA ...

Endothelial Senescence: A New Age in Pulmonary Hypertension

Cellular senescence impairs the reversibility of pulmonary arterial hypertension. Sci Transl Med. 2020;554:eaaw4974. doi: 10.1126 ...

Potential role of cellular senescence in pulmonary arterial ...

Cellular senescence impairs the reversibility of pulmonary arterial hypertension. Sci Transl Med. 2020; 12(554): eaaw4974.

Identification and experimental verification of senescence-related ...

However, a recent study found that elimination of senescent endothelial cells by senolytic drug impaired the control of pulmonary vascular cell ...

Making Sense of the Estrogen Paradox in Pulmonary Arterial ...

Is Pulmonary Arterial Hypertension a Cancer? Adriano R. Tonelli, Sci Transl Med, 2013. Cellular senescence impairs the reversibility of ...

Publications | Rabinovitch Laboratory for Cardiopulmonary Research

Stem Cell Res. 2020 Jul;46:101803. Cellular senescence impairs the reversibility of pulmonary arterial hypertension van der Feen DE, Bossers GPL, Hagdorn ...

Cellular senescence in the pathogenesis of pulmonary arterial ...

reversibility of pulmonary vascular disease. Eur Heart J. (2017) 38 ... senescence and impairs insulin sensitivity. through senescence ...

RAB7 deficiency impairs pulmonary artery endothelial function and ...

Cellular senescence impairs the reversibility of pulmonary arterial hypertension. Sci Transl Med. 2020;12(554):eaaw4974. View this article ...

Pulmonary Arterial Hypertension with Senescence

Van Der Feen, Diederik E., Guido PL Bossers, and Quint AJ Hagdorn, et al. "Cellular senescence impairs the reversibility of pulmonary arterial hypertension." ...