Changes in intrahost genetic diversity according to lesion severity in ...

Human papillomavirus type 16 (HPV16) is the most common cause of cervical cancer, but most infections are transient with lesions not progressing to cancer.

This study aimed to explore the intrahost HPV16 genomic variation in longitudinal samples from HPV16-infected women with different cervical lesion severity.

Changes in intra-host genetic diversity according to lesion severity ...

When investigating how SNVs may vary over time within individuals, we found that most individuals kept the same SNV pattern in all their samples ...

Changes in intra-host genetic diversity according to lesion severity ...

NASA/ADS · Changes in intra-host genetic diversity according to lesion severity in longitudinal HPV16 samples.

Changes in intrahost genetic diversity according to lesion severity in ...

Single nucleotide variants (SNVs) and intrahost SNVs (iSNVs) were identified in the viral genomes. A majority of individuals had a unique set of ...

Changes in intra-host genetic diversity according to lesion severity ...

Pre-existing mutations present at low frequency allowed faster adaptation of the non-recombinant virus compared to the recombinant virus. We ...

Changes in intrahost genetic diversity according to lesion severity in ...

Single nucleotide variants (SNVs) and intrahost SNVs (iSNVs) were identified in the viral genomes. A majority of individuals had a unique set of SNVs and these ...

Intra-Host Diversity of SARS-Cov-2 Should Not Be Neglected

We found evidence of quasispecies diversity in 68% of the samples, 76% of which was nonsynonymous variants with a higher density in the spike (S) ...

Intrahost evolution leading to distinct lineages in the upper and ...

In this study, we investigate the intrahost evolution and genetic diversity that accumulated during a prolonged SARS-CoV-2 infection with the Omicron ...

Rounge-lab/iSNV_longitudinal_study - GitHub

R scripts used in the study "Changes in intra-host genetic diversity according to lesion severity in longitudinal HPV16 samples" ...

Within-host genetic diversity of SARS-CoV-2 lineages in ... - Nature

We studied samples from Comirnaty and CoronaVac vaccine breakthrough infections and found that vaccination may be associated with changed ...

Genome-Wide Patterns of Intrahuman Dengue Virus Diversity ...

Significant differences in intrahost diversity were detected between genes and also between antigenically distinct domains of the Envelope gene. Interestingly, ...

Impact of Vaccination on Intra-Host Genetic Diversity of Patients ...

The high transmissibility, rapid evolution, and immune escape of SARS-CoV-2 variants can influence the course of infection and, in turn, morbidity and ...

Intra-host dynamic variations in SARS-CoV-2 - Abstract - Europe PMC

This evolutional process was driven two determinant factors: stochastic process (e.g., genetic drift or features of recent epidemiology) and the ...

SARS-CoV-2 within-host diversity and transmission - Science

To understand within-host diversity, we quantified the number of intrahost single-nucleotide variants (iSNVs) in the full set of 1390 genomes, testing different ...

Within-Host Diversity of SARS-CoV-2 in COVID-19 Patients With ...

Analysis also revealed higher prevalence of some variants among severe cases. Most importantly, severe cases exhibited significantly higher ...

Inter-Versus Intra-Host Sequence Diversity of pH1N1 and ... - MDPI

Haplotype sharing was also noticed in all years, strongly suggesting haplotype transmission among patients infected during a specific influenza ...

Impact of Clinical Parameters in the Intrahost Evolution of HIV-1 ...

We observed that the within-host HIV-1B genetic diversity, nonsynonymous and synonymous mutation rates and selection pressures also changed among patients, ...

Patterns of within-host genetic diversity in SARS-CoV-2 | eLife

95.1% of samples show within-host mutations at detectable allele frequencies. Analyses of the mutational spectra revealed strong strand ...

Jean-Marc Costanzi - Authorea

Changes in intra-host genetic diversity according to lesion severity in longitudinal... Jean-Marc Costanzi, Milan Stosic S, Alexander Hesselberg Løvestad ...