Chapter 11. The Genetics of Glaucoma
Chapter 11. The Genetics of Glaucoma - EyeRounds
Several lines of evidence indicate that glaucoma has a genetic basis, that is, glaucoma is caused in part by defects in specific genes.
Genetic and genomic studies, including genome-wide association studies (GWAS) have accelerated the discovery of genes contributing to glaucoma, ...
Chapter 11. Glaucoma - AccessMedicine - McGraw Hill Medical
Glaucoma is an acquired chronic optic neuropathy characterized by optic disk cupping and visual field loss. It is usually associated with elevated ...
Chapter 11 What is Functional Genomics Teaching us about ...
Proposed Molecular Signature of Human Glaucoma ... Analyzing the data from all above reports, at the end of this study we have compiled a set of 40 genes which we ...
A Patient's Guide to Glaucoma - EyeRounds
Glaucoma emergency: Acute angle closure glaucoma Chapter 10. Childhood (pediatric, congenital) glaucoma Chapter 11. The Genetics of Glaucoma Chapter 12.
Genetics of Glaucoma | SpringerLink
Genes that predispose to glaucoma may influence intraocular pressure or degeneration of the optic nerve or both. The types of glaucoma inherited ...
For glaucoma, these genetic factors include changes in the DNA sequences (near or in the genes such as caveolin 1 and 2 (CAV1/CAV2), CDKN2B antisense RNA, TMCO1 ...
Glaucoma Genetics - PMC - PubMed Central
Mutations in specific genes are associated with the manifestations of open angle glaucoma (OAG), pseudoexfoliation glaucoma (XFG), congenital glaucoma, and the ...
Glaucoma | Vaughan & Asbury's General Ophthalmology, 19e
Read chapter 11 of Vaughan & Asbury's General Ophthalmology, 19e online now, exclusively on AccessMedicine. AccessMedicine is a subscription-based resource ...
Glaucoma Syndromes: Insights into Glaucoma Genetics and ... - MDPI
The genetics, ocular and systemic features, and current and future treatment strategies are discussed. Findings from rare diseases also uncover important genes ...
Primary open angle glaucoma genetics: The common variants and ...
TXNRD2, 22q11, Oxidative stress ; FOXC1, 6p25.3, Anterior segment dysgenesis ; ATXN2, 12q24.12, Neurodegeneration ; GAS7, 17p13, CA, IOP changes.
Glaucoma Genetics: Recent Advances and Future Directions
2 Early genetic linkage studies on familial and congenital glaucoma have revealed a handful of genes with a very strong effect on disease. These genes include ...
Genetic Risk of Primary Open-angle Glaucoma: Population-Based ...
Since then, many studies have been performed in selected families in which the familial aggregation, inheritance, and mode of transmission of glaucoma were ...
The Genetics and the Genomics of Primary Congenital Glaucoma
Among the eye anterior segment disorders, special attention is given to Glaucoma as it represents one of the major causes of bilateral blindness ...
Genome-wide meta-analysis identifies 127 open-angle glaucoma ...
Integration of multiple lines of genetic evidence support the functional relevance of the identified POAG risk loci and highlight potential ...
Glaucoma: genes, phenotypes, and new directions for therapy - JCI
To date, at least 29 genetic loci for various forms of glaucoma have been defined by linkage studies (8, 9), and 12 causative genes have been identified from ...
Large-scale multitrait genome-wide association analyses identify ...
Other significant genes identified in rare variant gene-based association analysis included FKBP9, LTBP2, COL2A1 and the well-known glaucoma ...
Chromosomal Rearrangements and Novel Genes in Disorders of ...
Chromosomal Rearrangements and Novel Genes in Disorders of Eye Development, Cataract and Glaucoma - Volume 11 Issue 4.
Molecular Genetics of Glaucoma | SpringerLink
The past 2 years have seen considerable progress in the characterization of genetic factors that cause various forms of glaucoma [1–14].
Chapter 11 What is Functional Genomics Teaching us about ...
... 8 Potential mechanisms of steroid-induced glaucoma have been extensively studied. 9,10 Glucocorticoid exposure affects the expression of numerous genes in ...