Characterization of cell|fate decision landscapes by estimating ...

Characterization of cell-fate decision landscapes by estimating ...

Time-specific modulation of gene expression during differentiation by transcription factors promotes cell diversity. However, estimating ...

Characterization of cell-fate decision landscapes by estimating ...

We present FateCompass, an integrative approach that utilizes single-cell transcriptomics data to identify lineage-specific transcription factors throughout ...

Characterization of cell-fate decision landscapes by estimating ...

Modulation of gene expression during differentiation by transcription factors promotes cell diversity. Despite their role in cell fate decisions ...

Characterization of cell-fate decision landscapes by estimating ...

Time-specific modulation of gene expression during differentiation by transcription factors promotes cell diversity. However, estimating their dynamic ...

Characterization of cell-fate decision landscapes by estimating ...

Cell Reports Methods, Volume 3. Supplemental information. Characterization of cell-fate decision landscapes by estimating transcription factor dynamics. Sara ...

Characterization of cell-fate decision landscapes by estimating ...

Despite their crucial role in cell fate decisions, no experimental assays allow the estimation of transcription factors' regulatory activity in a high- ...

Characterization of cell-fate decision landscapes by estimating ...

Characterization of cell-fate decision landscapes by estimating transcription factor dynamics ... Time-specific modulation of gene expression ...

Characterization of cell-fate decision landscapes by estimating ...

Characterization of cell-fate decision landscapes by estimating transcription factor dynamics. ... Time-specific modulation of gene expression ...

Characterization of cell-fate decision landscapes by estimating ...

Characterization of cell-fate decision landscapes by estimating transcription factor dynamics · Résumé · Domaines.

Characterization of cell-fate decision landscapes by estimating ...

Characterization of cell-fate decision landscapes by estimating transcription factor dynamics · List of references · Publications that cite this publication.

Characterization of cell-fate decision landscapes by estimating…

Characterization of cell-fate decision landscapes by estimating transcription factor dynamics #CellReportsMethods https://lnkd.in/ecdTFa3y.

Revealing Dynamic Mechanisms of Cell Fate Decisions From Single ...

We developed a multifunction new method, Topographer, to construct a “quantitative” Waddington's landscape of single-cell transcriptomic data. This method is ...

Deciphering landscape dynamics of cell fate decision via a ...

It also provides a more rigorous and robust way for accurate cell fate decision. The study not only validates the previous experimental results but also ...

Decoding the principle of cell-fate determination for its reverse control

In principle, the predetermined cell fates can be changed by altering the attractor landscapes of cells by rewiring the core regulatory circuits ...

Dynamical landscapes of cell fate decisions | Interface Focus

The developmental path of a cell was pictured as a ball rolling through a terrain of branching valleys with cell fate decisions represented by ...

Dynamic landscapes and statistical limits on growth during cell fate ...

Our analysis leads to a sharp bound on the time it takes for a population to grow to a target distribution of a certain size. We show how the ...

Deciphering driver regulators of cell fate decisions from single-cell ...

The Waddington landscape can be used to illustrate the dynamic process of a developmental system established by gene regulatory relationships.

A logic-incorporated gene regulatory network deciphers principles in ...

By examining the two driving modes, we can gain a better understanding and characterization of cell fate decisions, including in-vivo cell ...

Quantifying the Waddington landscape and biological paths ... - PNAS

The landscape framework also quantifies the possibility of reverse differentiation process such as cell reprogramming from differentiated cells back to the ...

Characterizing Cellular Differentiation Potency and Waddington ...

The energy landscape at single-cell resolution further confirmed that cell fate decision is progressively specified in a continuous process. Moreover, the ...