Characterizing the tumor microenvironment at the single|cell level ...

Characterizing the tumor microenvironment at the single-cell level ...

The immune microenvironment extensively participates in tumorigenesis as well as progression in osteosarcoma (OS).

Characterization of the tumor microenvironment by single-cell RNA ...

In cancer cells, a higher expression of CX3CL1, CD74, and MHC-II genes in MPR patients was found, indicating elevated immune cell recruitment ...

Single cell genomic characterization reveals the cellular ...

The tumor microenvironment (TME) consists of a heterogenous cellular milieu that can influence cancer cell behavior. Its characteristics have an impact on ...

Characterizing the tumor microenvironment at the single-cell level ...

We also found that major histocompatibility complex class I (MHC-I) molecules were downregulated in cancer cells. The findings indicated a reduction in tumor ...

Characterizing the tumor microenvironment of metastatic ovarian ...

This comprehensive approach helps unravel the interactions between the cells within metastatic ovarian tumors at single-cell resolution. The ...

Metabolic landscape of the tumor microenvironment at single cell ...

The tumor milieu consists of numerous cell types each existing in a different environment. However, a characterization of metabolic ...

Unbiasedly decoding the tumor microenvironment with single-cell ...

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignant tumor characterized by a dismal prognosis, limited treatment response, ...

Characterizing the biology of primary brain tumors and their ...

Genetic variation at the single-cell level can be characterized using single-cell whole-genome sequencing (scWGS) methods, which provide ...

Single-cell spatial multiomics reveals tumor microenvironment ...

A myriad of different malignant and non-malignant cell types within the tumor contribute to immunotherapy response or resistance; however, the nature of these ...

Single-cell RNA sequencing reveals the tumor microenvironment ...

Tumor cell-intrinsic mechanisms and complex interactions with the tumor microenvironment contribute to therapeutic failure via tumor ...

scCancer2: data-driven in-depth annotations of the tumor ...

Single-cell RNA-seq (scRNA-seq) is a powerful technique for decoding the complex cellular compositions in the tumor microenvironment (TME).

Single-cell analyses of renal cell cancers reveal insights into tumor ...

A focused analysis of distinct cell-type compartments reveals the potential role of tumor epithelia in promoting immune infiltration and other ...

Single-cell signatures identify microenvironment factors in tumors ...

Tumor cells are surrounded by a microenvironment of various types of cells such as stromal and blood cells. Characterizing the composition and ...

Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor ...

Knowledge of immune cell phenotypes in the tumor microenvironment is essential for understanding mechanisms of cancer progression and ...

Characterizing the tumor microenvironment of metastatic ovarian

Interrogating tumor infiltrating lymphocytes at the single cell level. 504 also feature unique differences in other tumor infiltrating immune cells that are ...

Deciphering Innate Immune Cell-Tumor Microenvironment Crosstalk ...

The precise characterization of innate immune cells at the single-cell level will boost the potential of cancer immunotherapy. With the ...

The Application of Single-Cell RNA Sequencing in the Inflammatory ...

In recent decades, research on the tumor microenvironment (TME) has changed the traditional view of tumor treatment centered on tumor cells. The initiation and ...

Breaking the Immune Complexity of the Tumor Microenvironment ...

In this review, we describe some of the current single-cell technologies and computational techniques applied for immune-profiling the cancer landscape.

Characterizing the role of the immune microenvironment in multiple ...

... microenvironment in multiple myeloma progression at a single-cell level ... CD8(+) T cell states in human cancer: insights from single-cell analysis . Nat ...

Computational approaches for characterizing the tumor immune ...

The biological basis for the success or failure of immunotherapies rests in the complex interplay between malignant cells and the immune and ...