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Chitosan nanoparticles for oral drug and gene delivery


Chitosan nanoparticles for oral drug and gene delivery - PMC

Chitosan is a widely available, mucoadhesive polymer that is able to increase cellular permeability and improve the bioavailability of orally administered ...

Chitosan nanoparticles for oral drug and gene delivery - PubMed

Chitosan is a widely available, mucoadhesive polymer that is able to increase cellular permeability and improve the bioavailability of orally administered ...

Chitosan Nanoparticles as Oral Drug Carriers - MDPI

Natural polymers such as chitosan, albumin, and heparin have been used for the delivery of oligonucleotides, DNA, and proteins, as well as drugs ...

Chitosan in Oral Drug Delivery Formulations: A Review - MDPI

Various chitosan-based delivery systems, such as microparticles, nanoparticles, liposomes, and niosomes have been developed to deliver proteins ...

[PDF] Chitosan nanoparticles for oral drug and gene delivery

A review of studies on the formulation and oral delivery of chitosan nanoparticles shows their efficacy in enhancing drug uptake and promoting gene ...

Recent advances in chitosan-based nanoparticles for oral delivery ...

☆ This review is part of the Advanced Drug Delivery Reviews theme issue on “Nanoparticle- and biomaterials-mediated oral delivery for drug, gene, and ...

Chitosan-based nanoparticulate systems for oral drug delivery

Due to mucoadhesive property, chitosan nanoparticles can enhance oral bioavailability of drugs due to their increased residence time within the gastrointestinal ...

Oral gene delivery with chitosan–DNA nanoparticles generates ...

Chitosan is a biocompatible and slowly biodegradable polymer that has been widely used in controlled drug delivery18,19,20,21,22,23, and it may provide a less ...

Current Advances in Chitosan Nanoparticles Based Oral Drug ...

The unique physicochemical properties of chitosan polymer assist to overcome oral drug delivery barriers and target the colon tumour cells.

Chitosan Nanoparticles in Oral Drug Delivery - ChemRxiv

This review is concentrated on chitosan nanoparticles (CSNPs), which are derived from chitosan, a polysaccharide that is biodegradable and offers a promising ...

A comprehensive review of oral chitosan drug delivery systems

To improve chitosan properties, chemical and physical modifications have been developed, and recently, nanoparticles, microparticles, and beads ...

Oral drug delivery using a polymeric nanocarrier - RSC Publishing

The chitosan nanoparticle system ensures a burst delivery efficiency of 75% of rifampicin at a simulated intestinal pH over a period of 24 hours.

K. Bowman, K. W. Leong, “Chitosan nanoparticles for oral drug and ...

K. Bowman, K. W. Leong, “Chitosan nanoparticles for oral drug and gene delivery,” Int. J. Nanomed., 2006, vol. 1, pp. 117–128. ... ABSTRACT: An in-situ reactor ...

(PDF) Chitosan Nanoparticles as Oral Drug Carriers - ResearchGate

The physicochemical properties of chitosan give it the ability to form nanoparticles through multiple mechanisms, which will be addressed in this article. The ...

Advances and applications of chitosan-based nanomaterials as oral ...

In recent years, chitosan-based nanocarriers have emerged as potential carriers for oral delivery of drugs ranging from small hydrophobic molecules to proteins ...

[Article Metrics] Chitosan nanoparticles for oral drug and gene delivery

Chitosan nanoparticles for oral drug and gene delivery ; Sep 2012, 729, 0 ; Oct 2012, 887, 0 ; Nov 2012, 1,061, 0 ; Dec 2012, 1,199, 0.

Chitosan DNA nanoparticles for oral gene delivery

From administration at the oral cavity, chitosan nanoparticles must traverse the gastrointestinal tract and protect its DNA contents from significant jumps in ...

Chitosan nanoparticles for oral drug and gene delivery.

Clinical prospect of chitosan as a drug carrier and gene carrier. Y.-T. Wang zhong guo zu zhi gong cheng yan jiu yu lin chuang kang fu.2008, Vol. 12(10), p.

Chitosan Nanoparticles: A Promising System in Novel Drug Delivery

The chitosan nanoparticles, because of their biodegradability, biocompatibility, better stability, low toxicity, simple and mild preparation methods, offer a ...

Chitosan in Oral Drug Delivery Formulations: A Review

Studies have shown that controlled-release systems using nanoparticles composed of biodegradable natural polymers significantly improve oral administration, ...