Circadian oscillations persist in low malignancy breast cancer cells

Epidemiological studies have shown that humans with altered circadian rhythms have higher cancer incidence, with breast cancer being one of the most cited ...

Circadian Oscillations Persist in Low Malignancy Breast Cancer Cells

Request PDF | Circadian Oscillations Persist in Low Malignancy Breast Cancer Cells | Epidemiological studies have shown that humans with altered circadian ...

Circadian clocks and breast cancer

One of the processes regulated by the circadian clock is the cell cycle. Disruption of circadian rhythms can therefore be associated with ...

Tumor circadian clock strength influences metastatic potential and ...

Studies in shift workers and model organisms link circadian disruption to breast cancer. However, molecular circadian rhythms in noncancerous and cancerous ...

Circadian Oscillations Persist in Cervical and Esophageal Cancer ...

Studies have shown that cancer cells in general commonly display a disrupted circadian rhythm or exhibit deregulated circadian clock gene expression (8), where ...

Circadian clock: a regulator of the immunity in cancer

The exist circadian rhythm and the core circadian gene Bmal1, persist in malignancy breast cancer cells [61]. Tumor hypoxia-induced acidosis ...

Altered Circadian Rhythms and Breast Cancer: From the Human to ...

Breast, colon, prostate, lung, and ovarian cancers and hepatocellular carcinoma have all been linked in one way or another with altered circadian rhythms.

Analyses of BMAL1 and PER2 Oscillations in a Model of Breast ...

To reveal the systematic interactions between circadian rhythms and malignant transformations at the cellular level, several studies have ...

Circadian Alterations Increase with Progression in a Patient-Derived ...

Circadian rhythm disruption can elicit the development of various diseases, including breast cancer. While studies have used cell lines to study ...

Circadian clock features define novel breast cancer subtypes and ...

The circadian clock regulates key physiological processes, including cellular responses to DNA damage. Circadian-based therapeutic strategies ...

Interactions of circadian clock genes with the hallmarks of cancer

A strong relationship between circadian rhythm genes and various tumors, such as pancreatic, ovarian, lung, prostate, breast, colorectal, liver, non-Hodgkin's ...

Time-of-day effects of cancer drugs revealed by high-throughput ...

Consistent with our previous analysis, U-2 OS cells show strong circadian signal with the lowest noise levels (< 1%) and the highest proportion ...

Entrainment of breast (cancer) epithelial cells detects distinct ...

Next, we set out to test whether the circadian oscillation of clock gene expression is present in two ERA-positive breast cancer cell lines, T47D and MCF7, as ...

Circadian clock and cancer: From a viewpoint of cellular differentiation

Another study found that circadian gene expression rhythms are disrupted in high-grade basal MDA-MB-231 breast cancer cells, but not in low- ...

Daytime orexin and night-time melatonin regulation of mitochondria ...

(2019) Circadian oscillations persist in low malignancy breast cancer cells. Cell Cycle. 18 (19): 2447-2453. doi:10.1080/15384101.2019 ...

Post-transcriptional repression of circadian component CLOCK ...

Studies on cancer therapy reveal the presence of heterogeneous cells, including breast cancer stem-like cells (BCSCs), in breast tumors. BCSCs ...

Analyses of BMAL1 and PER2 Oscillations in a Model of Breast ...

Taken together, our data support that there are circadian discrepancies between normal and malignant cells, but it is difficult and insufficient ...

Circadian oscillations persist in cervical and esophageal cancer ...

... circadian clock gene promoters in breast cancer and ovarian cancer cells 36,37. ... Circadian oscillations persist in low malignancy breast cancer cells. Cell ...

Stromal Expression of the Core Clock Gene Period 2 Is Essential for ...

A disrupted circadian clock is associated with tumorigenesis, and cancer cells are thought to express a less robust clock compared to non-malignant cells (Welsh ...

PER2 Circadian Oscillation Sensitizes Esophageal Cancer Cells to ...

Here, we characterized the consequences of the daily oscillations of the clock-related gene PER2 in esophageal cancer cells and found that ...