Cisplatin|Associated Nephrotoxic Effects in Children

Cisplatin-Associated Nephrotoxic Effects in Children - JAMA Network

Persistent nephrotoxicity during 10-year follow-up after cisplatin or carboplatin treatment in childhood: relevance of age and dose as risk factors.

Cisplatin-Associated Nephrotoxic Effects in Children - PubMed

Cisplatin-Associated Nephrotoxic Effects in Children.

Cisplatin-induced nephrotoxicity in children: what is the ... - PubMed

Unfortunately, children receiving cisplatin-based chemotherapy have been known to be at risk for severe disabling adverse effects, such as ...

Cisplatin-induced nephrotoxicity in children: what is the best ...

Unfortunately, children receiving cisplatin-based chemotherapy have been known to be at risk for severe disabling adverse effects, such as ...

Acute Kidney Injury During Cisplatin Infusions in Children Treated ...

These factors could contribute to high AKI risk for neuroblastoma and central nervous system tumors. Synergistic nephrotoxic effects with other ...

Long-term cisplatin nephrotoxicity after childhood cancer

Cisplatin is a chemotherapeutic drug commonly used in the treatment of many childhood solid malignancies. It is known to cause long-term ...

Identifying cisplatin-induced kidney damage in paediatric oncology ...

This review article discusses the effect of cisplatin-induced nephrotoxicity (Cis-N) in children and considers the underlying mechanisms. We ...

Cisplatin Toxicity in Children with Malignancy

However, cisplatin-based treatments are limited by the risk of severe and progressive toxicities, such as oto- or nephrotoxicity, that can be ...

Renal toxicity and chemotherapy in children with cancer

The nephrotoxicity associated with the use of cisplatin in childhood cancer therapy has been demonstrated for some time, while recent studies ...

Cisplatin-Associated Nephrotoxic Effects in Children - ResearchGate

Cisplatin-Associated Nephrotoxic Effects in Children ... Content may be subject to copyright. ... based chemotherapy and are often prohibitive of ...

potential treatments for cisplatin-induced nephrotoxicity - Nature

The nephrotoxic effect of cisplatin is cumulative and dose dependent and often necessitates dose reduction or withdrawal. Recurrent episodes of ...

Early and late adverse renal effects after potentially nephrotoxic ...

Nephrotoxicity is a known side effect of several treatments, including cisplatin, carboplatin, ifosfamide, radiotherapy and nephrectomy, and can ...

Partial reversibility of cisplatin nephrotoxicity in children

We conclude that most children have some recovery from cisplatin glomerular toxicity, especially if damage is not severe, but that hypomagnesemia may persist.

Cisplatin dose rate as a risk factor for nephrotoxicity in children

Follow-up studies revealed partial recovery of GFR (P < 0.05). Glomerular and proximal nephron toxicity are common in children treated with ...

Renal toxicity of cisplatin in children - ScienceDirect

Cisplatin nephrotoxicity: The effect of dose, schedule, and hydration scheme. DentinoM et al. Long-term effect of cis-diamminedichloride platinum (CDDP) on ...

Cisplatin Nephrotoxicity and Longitudinal Growth in... - Medicine

Our study confirms a high frequency (76%) of nephrotoxicity in cisplatin-treated children. In order to evaluate the cisplatin nephrotoxicity we propose a score ...

Cisplatin-induced nephrotoxicity in childhood cancer - Europe PMC

Various definitions used to describe cisplatin nephrotoxicity potentially lead to differences in determination of risk factors. This study ...

Nephrotoxicity of Cancer Treatment in Children - Page 6 - Medscape

The clinical consequences of cisplatin nephrotoxicity include ARF, CRF and more commonly hypomagnesemia, which may cause paresthesia, tremor, tetany and ...

Genetic Variations and Cisplatin Nephrotoxicity: A Systematic Review

Background: Nephrotoxicity is a notable adverse effect in cisplatin treated patients characterized by tubular injury and/or increased serum creatinine (SCr) ...

Developing better mouse models to study cisplatin-induced kidney ...

These studies indicate that the nephrotoxic side effects of cisplatin treatment are long-lasting, and GFR remains decreased in a large percentage of pediatric ...