Cisplatin|induced nephrotoxicity in childhood cancer

Cisplatin-induced nephrotoxicity in childhood cancer - PubMed

This study evaluated incidence of kidney injury according to commonly used and alternative definitions in two cohorts of children who received cisplatin.

Long-term cisplatin nephrotoxicity after childhood cancer

In conclusion, this meta-analysis was impeded by heterogeneity but suggests that 29% of children treated with cisplatin will develop a reduction ...

Cisplatin-Associated Nephrotoxic Effects in Children - JAMA Network

Cisplatin has been an important component of chemotherapy for cure and control of several pediatric and adult malignant tumors. Nephrotoxic ...

Cisplatin-induced nephrotoxicity in childhood cancer

This study evaluated incidence of kidney injury according to commonly used and alternative definitions in two cohorts of children who received cisplatin.

Cisplatin-induced nephrotoxicity in children: what is the best ...

Unfortunately, children receiving cisplatin-based chemotherapy have been known to be at risk for severe disabling adverse effects, such as ...

Cisplatin dose rate as a risk factor for nephrotoxicity in children

... cisplatin nephrotoxicity in children. A total of 35 children underwent ... Evaluation of kidney dysfunction in childhood cancer survivors.

Acute Kidney Injury During Cisplatin Infusions in Children Treated ...

Cancer type and preinfusion kidney function were significantly associated with acute kidney injury risk at earlier and later infusions, and ...

Cisplatin Toxicity in Children with Malignancy

However, cisplatin-based treatments are limited by the risk of severe and progressive toxicities, such as oto- or nephrotoxicity, that can be ...

Identifying cisplatin-induced kidney damage in paediatric oncology ...

The kidneys are particularly susceptible to cisplatin toxicity, as they are almost exclusively responsible for its excretion. The UK Renal ...

Renal toxicity and chemotherapy in children with cancer

Renal toxicity may be manifested as a reduction of the glomerular filtration rate, electrolyte imbalances, or acute renal failure.

Persistent nephrotoxicity during 10-year follow-up after cisplatin or ...

Cisplatin is highly effective and has an important role in the treatment of children with neuroblastoma, osteosarcoma and some brain tumours, but chronic ...

(PDF) Long-term cisplatin nephrotoxicity after childhood cancer

It is known to cause long-term nephrotoxicity, most commonly manifesting as reduced glomerular filtration rate and hypomagnesaemia. Existing ...

Partial reversibility of cisplatin nephrotoxicity in children

We conclude that most children have some recovery from cisplatin glomerular toxicity, especially if damage is not severe, but that hypomagnesemia may persist.

Evaluation of kidney dysfunction in childhood cancer survivors

Despite this increase, childhood cancer survivors (CCS) are at high risk of developing late complications such as nephrotoxicity due to ...

Cisplatin Nephrotoxicity and Longitudinal Growth in... - Medicine

Cisplatin, a major antineoplastic drug used in the treatment of solid tumors, is a known nephrotoxin. This retrospective cohort study evaluated the prevalence ...

Long-term cisplatin nephrotoxicity after childhood cancer - OUCI

Abstract Background Cisplatin is a chemotherapeutic drug commonly used in the treatment of many childhood solid malignancies. It is known to cause long-term ...

Late Kidney Effects of Childhood Cancer and Cancer Therapies

Early case series of cisplatin nephrotoxicity showed that hypomagnesemia may persist in up to 30% of children by 2.5 years after completion of treatment, ...

Risk factors for cisplatin‐induced long‐term nephrotoxicity in ...

Although CPL-induced long-term nephrotoxicity was found in half of the pediatric CS of solid tumors, clinically significant nephrotoxicity was ...

Cisplatin-induced Nephrotoxicty and its Predisposing Factors for ...

Risk factors of nephrotoxicity includes age above 50, hypertension, and NSAID while hypertension and female gender are risk factor for not recover above 75% ...

Nephrotoxicity of Cancer Treatment in Children - Page 6 - Medscape

The clinical consequences of cisplatin nephrotoxicity include ARF, CRF and more commonly hypomagnesemia, which may cause paresthesia, tremor, tetany and ...