Clinical Practice of Monogenic Diabetes

Diagnosis and Clinical Management of Monogenic Diabetes - NCBI

There are two main clinical phenotypes of monogenic diabetes- neonatal diabetes (also called congenital diabetes) and MODY (Maturity-Onset ...

Monogenic Diabetes (MODY & Neonatal Diabetes Mellitus) - NIDDK

What causes monogenic diabetes? · affect how the pancreas develops · cause the pancreas to produce insulin that does not work well · destroy cells in the pancreas ...

The use of precision diagnostics for monogenic diabetes - Nature

The evidence underpinning the link between the genetic test result and clinical management and prognostics are covered as separate systematic ...

Approach to the Patient with MODY-Monogenic Diabetes

The presence of clinical features with 3 (or more) negative antibodies may be indicative of MODY-monogenic diabetes, and is followed by genetic testing.

Clinical Practice of Monogenic Diabetes | Frontiers Research Topic

Clinical Practice of Monogenic Diabetes ; Case Report. 30 May 2023 · Conghui Cao · 1 more · Xiaoli Wang ; Original Research. 23 March 2023 · Francesca Harrington · 4 ...

Monogenic diabetes: recent updates on diagnosis and precision ...

ing and treating clinical phenotypes associated with monogenic diabetes. ... ISPAD Clinical Practice Con- sensus Guidelines 2018: the diagnosis ...

Monogenic Diabetes: From Genetic Insights to Population-Based ...

However, the growing understanding of monogenic diabetes alone will not lead to much change in clinical practice. Practical application of ...

Monogenic diabetes: a gateway to precision medicine in diabetes - JCI

In a randomized clinical trial, low doses of sulfonylureas (e.g., 20–40 mg gliclazide daily) produced better glucose control than metformin in ...

Practical Aspects of Monogenic Diabetes: A Clinical Point of View

This article focuses on monogenic diabetes and neonatal diabetes. Maternally inherited diabetes and deafness (MIDD) have been reviewed elsewhere.

Editorial: Monogenic diabetes: from genetics and cell biology to ...

Monogenic diabetes is under-diagnosed. Awareness of clinical presentations of monogenic diabetes is a prerequisite for recognition of the condition, and ...

Monogenic diabetes: recent updates on diagnosis and precision ...

Precise medication for monogenic diabetes is based on genetic testing; therefore, an accurate diagnosis is essential. Due to the basic clinical ...

Monogenic Diabetes | Endocrine Society

Monogenic diabetes is a rare condition resulting from mutations (changes) in a single gene. In contrast, the most common types of diabetes—type ...

Syndromic Monogenic Diabetes Genes Should Be Tested in ...

In conclusion, mutations in syndromic monogenic diabetes genes are common in patients with suspected MODY in routine clinical practice. We ...

Next- generation sequencing is an effective method for diagnosing ...

Monogenic diabetes (MD) is a heterogeneous group of disorders caused by mutations in a single gene, most of which regulate pancreatic β cells function. MD ...

6687 New indication for monogenic diabetes genetic testing in ...

Methods We conducted a study of 1093 children with diabetes across seven paediatric diabetes clinics. The diabetes related clinical features, islet autoantibody ...

The diagnosis and management of monogenic diabetes in children ...

Monogenic diabetes results from the inheritance of a mutation or mutations in a single gene. It may be dominantly or recessively inherited or may be a de novo ...

Monogenic Diabetes | The University of Chicago

Monogenic diabetes is a category of diabetes caused by a single genetic abnormality. The main sub-categories are neonatal diabetes and maturity-onset diabetes ...

Precision diabetes: learning from monogenic diabetes | Diabetologia

MODY: slow uptake into clinical practice ... The recognition of MODY has been slow despite MODY being relatively common, the technology for ...

Monogenic Diabetes: A Comprehensive Overview and Therapeutic ...

Neonatal diabetes mellitus (NDM) is a medical disorder characterized by the onset of diabetes in individuals under six months of age. Infantile or neonatal ...

Monogenic Diabetes: A Diagnostic Algorithm for Clinicians - MDPI

Monogenic forms of beta cell diabetes account for approximately 1%–2% of all cases of diabetes, yet remain underdiagnosed. Overlapping clinical features ...