Clinical and biological insights from viral genome sequencing

Clinical and biological insights from viral genome sequencing - Nature

In this Opinion article, we will address the challenges and opportunities for making WGS, using modern next-generation sequencing (NGS) methods, standard ...

Whole-genome sequencing (WGS) of pathogens is becoming increasingly important not only for basic research but also for clinical science and practice.

Clinical and biological insights from viral genome sequencing - CORE

Metagenomic sequencing is most appropriate for diagnostic sequencing of unknown or poorly characterised viruses, PCR amplicon sequencing works well for short ...

1 Clinical and biological insights from viral genome sequencing 1 2 ...

Figure 1: Major methods for sequencing viral genomes from clinical specimens. 538. All specimens originally comprise a mix of host (in blue) and pathogen ...

(PDF) Clinical and biological insights from viral genome sequencing

PDF | Whole-genome sequencing (WGS) of pathogens is becoming increasingly important not only for basic research but also for clinical science and.

Clinical and biological insights from viral genome sequencing

Whole-genome sequencing (WGS) of pathogens is becoming increasingly important not only for basic research but also for clinical science and practice. In ...

Clinical and biological insights from viral genome sequencing - Apollo

Whole-genome sequencing (WGS) of pathogens is becoming increasingly important not only for basic research but also for clinical science and practice.

Clinical and biological insights from viral genome sequencing

Sequencing viral DNA and RNA is an important part of clinical practice, although, so far, mostly subgenomic fragments have been sequenced.

Clinical and biological insights from viral genome sequencing - OUCI

Depledge, D. P. et al. Specific capture and whole-genome sequencing of viruses from clinical samples. PLoS ONE 6, e27805 (2011). https://doi.org/ ...

Viral genome sequencing methods: benefits and pitfalls of current ...

Whole genome sequencing of viruses provides high-resolution molecular insights, enhancing our understanding of viral genome function and ...

A collaborative approach to improve representation in viral genomic ...

New SARS-CoV-2 variants are detected and tracked using viral genomic surveillance, an approach wherein the genomes from circulating viruses are sequenced, ...

What Novel Sequencing Methods Are Teaching Us About ...

43. Houldcroft CJ, Beale MA, Breuer J. 2017.. Clinical and biological insights from viral genome sequencing. . Nat. Rev. Microbiol. 15:(3): ...

Viral genomics in Ebola virus research | Nature Reviews Microbiology

Advances in the sequencing and functional characterization of both pathogen and host genomes have provided a wealth of knowledge to clinicians, ...

Viral Genome Sequencing

Deliverables · Houldcroft C J, Beale M A, Breuer J. Clinical and biological insights from viral genome sequencing. Nature Reviews Microbiology, 2017, 15(3): 183- ...

A complete protocol for whole-genome sequencing of virus from ...

Our protocol is able to generate the viral dominant genome sequence starting from clinical samples. It is based on a multiplex PCR amplicon sequencing coupled ...

Clinical and biological insights from viral genome sequencing - Gegnir

Sequencing viral DNA and RNA is an important part of clinical practice, although, so far, mostly subgenomic fragments have been sequenced.

A complete protocol for whole-genome sequencing of virus from ...

... genome sequencing of virus from clinical samples: Application to coronavirus OC43" by F. Maurier ... Clinical and biological insights from viral genome sequencing.

Genetic Surveillance of Five SARS-CoV-2 Clinical Samples in ...

The whole genome sequencing plays a crucial role in virus surveillance and evolutionary analysis. In this study, five genome sequences of SARS- ...

Viral Genomics | Broad Institute

optimizing sequencing for clinical viral samples · developing experimental and computational methods for rapid pathogen detection and diagnosis from genome data ...

Rapid implementation of SARS-CoV-2 sequencing to investigate ...

We combined epidemiological and genomic analysis of the 299 patients from our hospital and identified 35 clusters of identical viruses involving ...